DFine, Inc., founded in 2004, is a medical device company based in San Jose, California.
DFine's mission is to develop and market devices that treat vertebral compression fractures and other spinal disorders in a minimally invasive manner to improve patient quality of life.
DFine's RF Kyphoplasty procedure with the StabiliT™ Vertebral Augmentation System is the next generation in kyphoplasty. It combines the benefits of site-specific cavity creation, controlled cement delivery, and potential for height restoration with ultra-high viscosity bone cement. During the procedure, radiofrequency energy is applied to specially formulated energy-responsive bone cement to create an ultra-high viscosity cement. The cement is delivered into a cavity within the vertebra using a remote hand switch that allows the physician to remain up to 10 feet from the fluoroscopic field, potentially reducing the physician's exposure to radiation.
The first RF Kyphoplasty cases were conducted in Europe as part of the SPACE clinical study in December of 2006. US spine specialists began performing RF Kyphoplasty with the StabiliT™ Vertebral Augmentation System in April of 2008, while commercialization in Europe began in February of 2009 .