Onyx Pharmaceuticals, Inc. (Onyx) is a biopharmaceutical company engaged in developing therapies that target the molecular mechanisms that cause cancer. With the Company’s collaborators, the Company is developing small molecule drugs. The Company develops oral anticancer therapies designed to prevent cancer cell proliferation and angiogenesis – more... by inhibiting proteins that signal or support tumor growth. The Company’s product, Nexavar (sorafenib) tablets, being developed with the Company’s collaborator Bayer HealthCare Pharmaceuticals (Bayer), is approved by the United States Food and Drug Administration (FDA), for advanced kidney cancer and liver cancer. Nexavar is a novel, orally available kinase and angiogenesis inhibitor and is one of a new class of anticancer treatments that target signaling pathways important to the proliferation of cancer cells. During the year ended December 31, 2007, Nexavar was approved for the treatment of patients with liver cancer.
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