Otsuka America is the holding company for the US operations of Japan's Otsuka Pharmaceutical. Otsuka America oversees pharmaceutical research and development, marketing, and distribution of both prescription drugs and over-the-counter (OTC) medicines. The company's pharmaceutical subsidiaries include Otsuka America Pharmaceutical (prescription drug marketing), Otsuka Maryland Medicinal Laboratories (research), Cambridge Isotope Laboratories (chemical ingredients), and Pharmavite (nutritionals). To help wash down its pills, Otsuka America also holds consumer beverage makers Crystal Geyser (bottled water), Ridge Vineyards (wine), and Soma Beverage Company (specialty bottled water).
Through its Otsuka America Pharmaceutical subsidiary, Otsuka America markets its Japanese parent's pharmaceutical products in North America, with a focus on neurology, oncology, cardiovascular, and gastrointestinal therapeutics. Primary products include Pletal (marketed as Pletaal in Asia) for the treatment of peripheral arterial disease, and Abilify (co-promoted with Bristol-Myers Squibb) used to treat schizophrenia and bipolar disorder. The company also sells some diagnostic tests and related equipment through its Meretek subsidiary.
Otsuka America has a full pipeline of drug candidates and seeks out potential products from other pharmaceutical companies. Research and development is conducted by subsidiaries Otsuka Maryland Medicinal Labs and Otsuka Pharmaceutical Development & Commercialization. Drug candidate Samsca (dehydration therapy) received FDA approval for US marketing in 2009. Aripiprazole and Tolvaptan, treatments for schizophrenia and kidney disease, respectively, are next up in the pipeline.
Japanese parent Otsuka Pharmaceutical further expanded Otsuka America's portfolio by acquiring rights to IV Busulfex, a bone marrow transplant therapy for oncology patients marketed in North America and other regions, from PDL BioPharma for $200 million in 2008. Otsuka Pharmaceutical intends to further expand its North American operations in the fields of pharmaceuticals and diagnostics. – less