The SlipChip product development program hinges on developing molecular and protein assays that are on par with the highest quality standards, yet functional in a limited resource setting. The platform will be capable of extracting nucleic acids and proteins from biological fluids and then quantifying them without use of electricity or significant user intervention.
The Senior Biologist will be responsible for designing and optimizing the chemistry and biological tools for performing NAAT, including NA purification, isothermal amplification and related detection methods. This person will coordinate with team members to develop a platform for sample-in-result-out tests that can be done in limited resource settings. The senior biologist will identify high impact targets and optimize user workflow. This person will need to have or develop and deep understanding of the latest technologies for testing in limited resource settings based on NAAT.
Ideally the successful candidate will have the following, though exceptions can be made for candidates with strong characteristics in other areas:
1. Ph.D. in molecular biology, biochemistry or related fields, 5+ year experience (academia or industrial) in molecular biology, and clinical diagnostics is highly desired.
2. Expertise in experiment design, optimization, and trouble shooting;
3. Expertise with sample preparation of nucleic acid and protein biomarkers from different types of samples, such as blood, urine, and swab is preferred;
4. Expertise on isothermal amplification is preferred;
5. Expertise on single molecule detection is highly desired;
6. Experience in microfluidics or device/assay integration is a preferred.
SlipChip LLC is a microfluidics company with a proprietary platform to designed to make highly quantitative measurements of nucleic acids and proteins on plastic chips with minimal capital equipment. The platform is capable of performing standard PCR, RT PCR and digital PCR measurements and multiplexed reactions in both traditional and limited resource settings (LRS).