In Texas you are not supposed to work under the influence of any substances. So legally you are not allowed to take narcotic pain meds while working as a nurse. On the Texas application for licensure, they do ask as one of the questions if you have ever been diagnosed or treated for certain psychiatric conditions including bi-polar disorder. You then have to send a letter of explanation to the board. I am sure there are a number of nurses practicing who have your conditions, but you just may have to jump through an extra hoop to get you license. You should check out you state board of nursing website and ask them for specifics.