finding a job

I have been a nurse for 18 years. I have ALOT of experience in many different areas of nursing. Im not used to going through hiring agencies, I am usually called from a facility or apply directly to that facility. I am not getting responces, as I would have thought with the job qualifications I have as a seasoned nurse. I am trying to move permenately to an area, and finding a job is definately putting everything on hold and I have already given a months notice to move out of the home I rent. I am optimistic most all the time, but this process is wearing me out!