What a nice dilemma to be in, if you think about it.
The first question I would ask you is, WHY did you leave the former employer in the first place? Has the reason why you left changed? If the reason was the job or a person, it may very well be fine to return. If the reason was the company, the owner, the culture, etc., it likely has not changed. That would be the first thing I would consider.
For you job you're doing at home and loving, can you expand on it to earn more money, or do adjust it in some way that will allow you to use your nursing degree? If so, explore that option first. It's rare that we have jobs we love.
At the end of the day, this is a classic pro/con listing issue. What will you be giving up and gaining to take the DON job versus your current job?