Database Architect
Children's Hospital Philadelphia - Philadelphia, PA

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- 5 to 10 years of experience using Postgres, Oracle, MySQL, MongoDB, CouchDB, or other alternative database technologies in a large-scale development and production environment.
- Experience working on data warehousing projects, scientific or clinical preferred.
- Experience modeling highly dimensional data types such as those derived from next generation sequencing, micro array, and genotyping assay data preferred
- Experience modeling multiple complex data types – e.g. transactional, non-transactional, factless.
- Track record of success working with stakeholders, analysts, and software developers in multidisciplinary teams focused on multi-tier development and production systems.
- Able to determine and communicate the value of various database technologies in the context of a complete solution
- Experience with critical evaluation and selection of the best of multiple alternative technologies for a given job
- Demonstrated track record of balancing high-availability and cost, given the nature of an application
- Expertise with performance evaluation, benchmarking and optimization
- Expertise with tuning performance of both read and write operations

Mandatory Requirements:
All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.
• Child Abuse Clearances
• FBI Fingerprint Clearance
• Drug Screening

Job Description:
Since its inception in 2006, analysts and programmers at The Center for Biomedical Informatics (CBMi) at The Children’s Hospital of Philadelphia (CHOP) have promoted and enabled the innovative use of next generation sequencing to benefit the health of both our patients and the general pediatric population. To that end, CBMi is now looking for progressive and talented informatics professionals to develop an expanded next generation sequence-based clinical diagnostics framework in collaboration with CHOP’s Department of Pathology and Laboratory Medicine. The resulting system, which includes raw data processing, data management and archiving, summary data views, algorithm-based decision support, and other analytical modules, will be used to better diagnose and treat specific heritable disorders and pediatric cancers.

The Database Architect will create novel data storage and retrieval solutions that make it possible to perform whole genome diagnostics for pediatric patients. The successful candidate will design, implement, and administer petabyte-scale database systems that are intrinsic to bioinformatics analysis pipelines, annotation services, analytic applications, and clinical decision support tools. The Database Architect will define and execute a technical and implementation strategy as a key contributor to CHOP’s goal of providing cutting-edge genome-enabled care to our pediatric patients. Expert knowledge of multiple RDBMS, noSQL, and file-based database technologies is critical, as is the ability to combine multiple database technologies to achieve system design goals. Experience in both development and production environments is a must, along with a team- and results-oriented attitude.

About this company
The Children's Hospital of Philadelphia (CHOP) is the nation's first hospital devoted exclusively to the care of children. Since our start...