Director, Head of Cellular Immunology
Merck - Billerica, MA

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PURPOSE OF THE ROLE

Contribute to the development and implementation of EMD
Serono research strategy within Immunology Discovery with focus
on auto-antibody-mediated diseases.

Contribute to the scientific excellence of Immunology
Discovery and Translational Research function.

Plan, direct and control the departmental research
activities leading to new or improved drug targets and
candidate drug products or processes.

Manage a team of scientists, specialists and technicians,
where appropriate through unit heads.

Be responsible, together with the other Research Department
Heads, for the effective running of a matrix system of project
management and of quality management system.

Contribute to local management through proactive
participation in local committees

MAIN INTERFACES

INTERNALLY

:

Other members of

Discovery Senior management team and Discovery board, Merck
Serono worldwide R&D scientific professionals

Within Immunology on a regular basis: Project teams; Depts
of Exploratory Immunology, in vivo pharmacology and Clinical
Immunology.

Outside Immunology as needed: Scientists and/or project
teams from other Therapeutic Areas and platforms, Medicinal
Chemistry, CMC, DMPK-Tox-Safety Pharmacology, IP, Business
Development, Operational Excellence (Portfolio – in licensing),
Exploratory Medicine, Medical and Marketing.

EXTERNALLY

:

International scientific experts and KOLs

CROs, academic groups and clinical centers

KEY TASKS & RESPONSIBILITIES

As member of the Immunology Leadership Team, the Head of
Cellular Immunology is responsible for the formulation and
execution of the R&D strategy in this area.

Prepare budget recommendations for the department and
sub-groups to Function Head and manage the budget within the
approved limits.

Transmit and dispatch decisions from the leadership team
to members of the department. To clearly elaborate the
research objectives to members of his Department in line with
the Immunology objectives and to monitor scientific
achievements and standards in his area of
responsibility.

Responsible for the productivity and discipline of
members of the department.

Ensure adequate training and coaching for the effective
execution of their duties, to carry out periodical
performance appraisals of direct reports and to review
performance appraisals done by line managers for other staff
within the department. Is also expected to give feedback on
other staff as required. To propose and discuss salary
recommendations with HR further to the appraisal
process.

Responsible for the allocation of resources and effective
execution of activities required for approved projects
originating within and outside the department and to develop
any new resource required. To supervise efficient tracking of
time and resources allocated per project within his
department and to make appropriate recommendations to
management as needed.

Effectively support discovery project teams by providing
a planning structure in the department that enables project
team members to effectively review project requests with
peers and build options to the project teams.

To serve as DPTL and team member of DPTs.

To build and maintain world-class expertise in the field
of cellular immunology and expand it to inflammatory diseases
of interest to the organization.

Participate to authorship of scientific and/or patent
publications.

Develop and maintain target and disease assays and models
to support the discovery of NCE and NBE as well as their
non-clinical evaluation.

Develop new techniques and potential areas of research
within his/her fields of responsibility, formulating new
project/target proposals, and initiating any necessary
exploratory research to allow evaluation of the target and/or
approach.

Ensure that all documentation standards are met and write
study reports on research activities as required.

Provide scientific hypotheses, technologies and
experimental data needed for translation of disease-relevant
biomarkers monitored
in vitro

to
in vivo

disease models and onwards to the clinic (PoC).

Establish external collaborations with key
experts/technologies and to drive academic, clinical research
collaborations or sponsor CROs to support the discovery and
development of NCE and NBE within the Immunology
Discovery.

Participate to cross-functional alignment of new business
effort within Immunology and contribute actively to selection
of new targets for autoimmune indications.

Participate to evaluations and due diligence missions for
in-licensing opportunities. Deliver written feedbacks and
reports.

As responsible for the safety, the Director must ensure
safe working conditions in the laboratories and the
maintenance of equipment and facilities to a high standard,
in compliance with internal or external regulations.

Together with VP Immunology establish a level of
excellence of the function and assist the VP with matters of
general research administration as required.

Qualifications

EDUCATION/ LANGUAGES

PhD in Immunology.
Trained in autoimmune diseases with considerable basic research
experience.

Fluency in spoken
and written English

PROFESSIONAL SKILLS & EXPERIENCE

Scientific level
corresponding at minimum to a Senior Scientist level

10-15 years of
postdoctoral experience with significant industry experience

Excellent
publication records and speaker invitations to major
international conferences

PERSONAL SKILLS & COMPETENCIES

Outstanding
communication and interpersonal skills

Proven management
competencies (leadership, influencing and decision making
skills)

Merck - 20 months ago - save job - block
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