DMPK Scientist
BioPhase Solutions - San Diego, CA

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BioPhase Solutions specializes in recruiting top talented professionals for San Diego's Scientific community. We are currently looking for a DMPK Scientist to work for a leading San Diego County biotechnology company.

DMPK Scientist

Our client is seeking an experienced DMPK scientist to conduct, lead and manage in vitro studies to understand and characterize the absorption, distribution and elimination of drug candidates. A thorough understanding of the theoretical and technical aspects of drug interaction studies and prediction of clinical implications is required. Experience with automation is preferred. Experience with metabolite identification and profiling studies in vitro systems (liver microsomes, S9, plasma, hepatocytes, etc.) and in vivo systems (mice, rat, dog, monkey, human) is a plus. Responsibilities include strategic input to Discovery Teams in order to advance compounds to preclinical candidate selection, and collaboration with other scientists and management in defining DMPK workstreams for specific drug candidates. The scientist will also be expected to perform related tasks and activities as assigned by the company. Strong experience in areas of in vitro ADME, mass spectrometry and HPLC is essential. The preferred candidate will also have demonstrated expertise in in vitro-in vivo correlation.

This position requires the successful candidate to generate, analyze and present data, both orally and as written reports. Knowledge of GLP, development and regulatory guidelines is required. The position may also require training and supervision of Research Associates. The ability to work independently, excellent communication and presentation skills are required.

PhD in bioanalytical chemistry or related field with 5+ years of industrial experience

Extensive knowledge of DMPK science, particularly in vitro ADME, and experience in applying DMPK concepts to drug discovery and drug development

Strong expertise in developing and troubleshooting LC-MS/MS methods and instrumentation

Ability to set up, validate and conduct new DMPK assays

Good organizational, record keeping, presentation and communication skills

Ability to work independently and within a team environment

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