BioPhase Solutions specializes in recruiting top talented professionals for San Diego's Scientific community. We are currently looking for a Downstream Processing Scientist to work for a leading San Diego biotechnology company.
Downstream Processing Scientist
Support all projects within company protein production and biopharmaceutical-based
businesses. Fully competent in and able to take responsibility for downstream process
development and technology transfer activity within these projects.
BS/MS/PhD in Biochemistry/Biochemical Engineering and 5-10 years of relevant experience
Experience in downstream process development and scale-up for biopharmaceutical protein production
Knowledgeable in protein biochemistry and analytical methods relevant to protein purification
Experience with operation of different modes of chromatography (ion-exchange, hydrophobic interaction, affinity, mixed mode, etc.) at laboratory and pilot scales
Experience with principles and operations of continuous centrifugation, microfiltration, ultrafiltration, cell disruption, membrane filtration at laboratory and pilot scales
Familiarity with GE Healthcare AKTA FPLC protein chromatography systems and software
Demonstrated ability to provide technical solutions for complex problems through the use of independent experimental design and product/process knowledge
Demonstrated ability to deliver presentations that distill complex ideas and proactively communicate results and progress to technical teams, management, and business leadership
Experience writing technical documents, including SOPs, batch records, technology transfer documents that describe protein manufacturing unit operations and processes.