Johnson & Johnson - San Diego, CA

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Janssen Research & Development, L.L.C., a Johnson & Johnson company is recruiting for a Principal Research Scientist for Molecular Profiling, located in La Jolla, CA.

Janssen Research & Development, L.L.C. is a fully integrated biopharmaceutical and biotechnology company. As a world leader in the field of biomedicines, Janssen strives to develop innovative treatments to improve the health of people worldwide. At the forefront of monoclonal antibody technology and manufacturing, Janssen Research & Development manufactures products including REMICADE® (infliximab), STELARA™ (ustekinumab) and SIMPONI™ (golimumab) for the treatment of various immunological diseases.

This position requires the individual to accelerate time to market of differentiated medicines for immunology through the use of informatics in driving innovation and enabling effective decision making. The successful candidate will have responsibility for leading molecular profiling for biomarkers within the Immunology therapeutic area.

The individual will have responsibility for ensuring internal data analysis methodologies and tools are current through external benchmarking, optimizing the data analysis process, influencing experimental design, ensuring the timely delivery of data analysis results, and effectively communicating the analysis approach and results to scientists. The individual will primarily guide the work of a team of data analysts, and will be responsible for their development and growth. The individual will at times be required to undertake data analysis.

This individual will have the opportunity to influence data analysis approaches across the broader Johnson & Johnson informatics community. The successful candidate will contribute to the overall direction of the Systems Pharmacology and Biomarkers team. In addition to technical acumen and a proven track record of results, this position requires outstanding communication and collaborative skills. The successful candidate will facilitate robust interactions with scientists from multiple areas within the immunology therapeutic area including informatics, biomarkers, discovery, and clinical. The individual is expected to maintain a state-of-the-art knowledge in computational biology and molecular profiling through participation in community activities and to develop substantial internal and external networks including domain experts and key opinion leaders in the computational biology and early drug discovery space.

Team members are encouraged to publish and to develop and maintain a strong professional network within the internal and external scientific communities.


A PhD in systems biology, computational biology, or bioinformatics or equivalent experience is required. 5-8 years of progressive scientific experience is required. The ability to apply data mining, machine learning, and emergent algorithms to pre-clinical, clinical and health outcomes data to generate new hypotheses is required. Experience in network analysis, modeling biological pathways, and simulation is required. Experience in investigating immune-related pathways/networks and/or diseases are preferred. Having a strong publication track record is required. Being a recognized industry expert with an established network of contacts is preferred. A strong track record of building effective and trusted partnerships with scientists is required. A track record of successfully forming and managing collaborations is required. This position is located in La Jolla, California.

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Primary Location: North America-United States-California-San Diego
Organization: Janssen Research & Development, LLC. (6084)

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