BioPhase Solutions specializes in recruiting top talented professionals for San Diego's Scientific community. We are currently looking for a Process Development Associate to work for a leading San Diego biotechnology company.
Process Development Associate
Carry out fermentation experiments
Read SOP (if not clear, discuss with a senior PDA/scientist). Update SOP based on discussion.
Prep various types of media: Add chemicals, Adjust to correct volume according to SOP
Sterilize medium/solutions using autoclave
Aseptically inoculate seed flasks and place into incubator shaker according to SOP.
Prepare bioreactor/tank for fermentation
Calibrate probes according to SOPs
Set up fermentation parameters and sterilize tanks according to SOP
Set up tank-hook up all external feed bottles, adjust pH and bias, add necessary ingredients according to SOP, double check fermentation parameters
Check the seed for contamination using the microscope
Inoculate tank - transfer seed into inoculation bottle and add to tank aseptically, start fermentation process
Sample fermentors according to SOP
Adjust parameters/shot size according to SOP
Perform aseptic techniques
End fermentations according to SOPs
Insure identified problems are communicated to Shift Supervisor and/or scientists.
Clean tanks according to SOP
Recording data in SOP and on Nexxis
Document bioreactor/needed solutions prep
Document fermentation parameters
Document any changes and anything unusual
Document final fermentation data
Document harvest label
Gather all documents and print out trends. (if requested)
Submit detailed shift reports.(if required)
Initial the pass down log for work completed
Log maintenance issues in Nexxis
Pilot plant housekeeping
Insure pilot plant and equipment are kept clean
Assist in checking chemical/supply inventory and notifying when items are needed
Enter chemicals in Chemical Inventory Manager and barcode container
Inform supervisor of maintenance issues and submit facilities requests for needed repairs
Assist in fixing/adjusting equipment and program applications (control temperatures, pressure, pH, etc.).
Assist with scientific troubleshooting (organism problems, feeding, etc. using trend data to identify possible solutions).
Assist in training lower level technicians/PDAs.
Other duties as assigned by Shift Supervisor or Pilot Plant Operations Manager
Requires BS/BA Degree in life sciences or equivalent education and/or fermentation experience
BioPhase Solutions - 15 months ago