The Ben Towne Center for Childhood Cancer Center seeks to hire an enthusiastic and team-oriented Research Scientist to manage the correlative studies of our pediatric cancer immunotherapy clinical trials. The successful candidate will be responsible for development, execution and rigorous data analysis and interpretation of multi-parametric flow cytometric-based assays to characterize and monitor the biological aspects of our adoptive immunotherapy with re-engineered T-cells in clinical trial samples. The candidate should have demonstrable experience serving as a technical scientific expert in flow cytometry with hands-on experience building and utilizing panels of reagents to characterize cellular populations using cell surface markers. The successful applicant will provide strong expertise and mentoring in T cell biology and flow cytometric analysis to support both our clinical manufacturing group and our research group. Additionally, this individual will be responsible for maintaining the daily operation of our flow cytometry core equipment, training equipment users, and maintaining the related consumable reagent inventory.
- PhD or M.D. in Molecular or Cellular Biology, Biochemistry, or other closely related field
- Minimum of four (4) years experience in required field of specialization
- Prior experience with laboratory management or other relevant research field.
- PhD in Immunology, Molecular or Cellular Biology or closely related field
- Minimum of four (4) years post-graduate experience
- Experience in T cell biological assays and routine cellular experimental procedures
- Strong background in flow cytometric assay development and data analysis preferably on BD flow cytometers (LSRII, LSRFortessa, Canto, Jazz)
- Hands-on cell sorting experience (BD Aria II or BD Aria III)
- Strong proficiency and working knowledge of FlowJo, BD FACSDiva and GraphPad Prisim software
- Has worked in a compliant laboratory environment (GLP, GMP, or CLIA)
- Strong Data collection, analysis, and summary skills
- Strong analytical and problem-solving skills
- Able to effectively coach, mentor and train junior staff and students in development of technical aspects of flow cytometry and T cell biological assays
- Experience with statistics and relevant computer programs
- Experience writing and editing manuscripts
- Excellent written and oral communication skills
- Knowledge of software applications, and proficiency using MS Office (Outlook, Word, Excel & Access)
- Knowledge of electrical and mechanical equipment maintenance.
- Excellent management and leadership skills
- Strong scientific writing skills
- Strong organizational skills, including the ability to prioritize work across projects
- Strong interpersonal skills, and ability to establish and maintain effective working relationships with a variety of people
- Able to work safely with radioactive and hazardous materials
Seattle Children's Hospital - 23 months ago
Children's Hospital and Regional Medical Center was a big name for little kids, so they changed it to what everyone already used:...