Research Scientist
Veterans Medical Research Foundation - San Diego, CA

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Qualifications Summary:
Master's degree or equivalent and at least two years of related experience; or equivalent combination of education and experience.

Job Description Summary:
Uses genomics technologies and bioinformatics to study HIV pathogenesis and latency. Develops a program in genomics, informatics and pathogenesis of viral diseases. Generates microarray gene and microRNA expression data. Analyzes gene expression in order to investigate the mechanism of disease or to identify biomarkers capable of diagnosing disease states, predicting disease outcomes, or tailoring therapies to the individual patient compared between highly active antiretroviral therapy (HAART)-treated HIV-infected patients who recover their immune system and those who do not, in order to determine the mechanism of immune recovery. Identifies prognostic biomarkers for post-traumatic stress disorder. Assesses blood gene expression for diagnosing Parkinson’s Disease. Employes machine learning classification to identify potential vaccine candidates in the genomes of pathogenic bacteria in a reverse vaccinology approach. Identifies genes modulated by Vitamin D that have antiviral properties. Analyzes the impact of stress on the immune system in a sky diving model. Identifies genes involved in resistance to infection with Coccidioides immitis. Performs a meta-analysis of six different microarray studies comparing gene expression in brain tissue between schizophrenic individuals and controls in order to reveal the mechanism of disease. Manages a research group. Investigates the off-target effects of histone deacetylase inhibitor (HDACi) induced gene expression changes in resting CD4+ T cells. Selects probes that can be used in small diagnostic field kits for the rapid identification of Influenza strains. Provides bioinformatic support for a variety of studies analyzing epidemiological, sequence, flow cytometry and gene expression data collected from the HIV cohort followed by the UCSD Antiviral Research Center (AVRC). Provides grant writing support as a faculty member to three different T32 training grant proposals. May perform additional duties as required.

Veterans Medical Research Foundation - 18 months ago - save job - block
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