BioPhase Solutions specializes in recruiting top talented professionals for San Diego's Scientific community. We are currently looking for a Sr. Research Associate I to work for a leading San Diego biotechnology company.
Sr. Research Associate I
Supports discovery projects by developing bioanalytical methods and performing analysis for all biologics programs.
Responsible for development of ligand-binding assays for large molecules
Develop immunoassay methods (ELISA, MSD, etc.) to quantify drug concentrations.
Develop immunoassay methods (ELISA, MSD, etc.) to assess presence of anti-drug antibodies in serum.
Prepares protocols for and conducts routine sample preparation and analysis of serum samples for PK and ADA analysis.
Will assist in preparation of technical reports or summaries.
May evaluate new techniques, technologies and equipment (LC-MS/MS, etc).
Assists in the implementation of new methods and processes.
Participates in the interpretation of scientific data.
With some guidance, plans, conduct, evaluate and interpret non-routine laboratory experiments.
Remains current with new practices and procedures in relevant literature.
Provides solutions to a variety of problems of moderate scope and complexity.
Collaborates and communicates within and across departments.
Responsible for maintaining accurate records of ongoing projects in a laboratory notebook.
May contribute to authorship of technical reports, manuscripts or posters.
May present data to cross-functional project team; may present data/posters at external or internal conferences.
Follow company safety procedures.
Maintains lab equipment and supplies as necessary.
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
BS/MS in Pharmaceutical Sciences/Chemistry/Biochemistry/Biology or related coursework and 5 years of relevant experience with a BS or a MS with 3 years experience.
Experience in the development and validation of immunoassays or molecular assays in industry or academic setting.
Experience with bioanalysis of drug levels and/or immunogenicity in a drug discovery environment a plus
Experience in multiple immunoassay techniques applicable to PK and immunogenicity studies a plus
Experience with LC-MS/MS analysis of proteins a plus
Experience with SoftMax Pro software.
Familiar with FDA and EMA Bioanalytical Method Validation Guidance.