Sr. Research Investigator
Purdue Pharma L.P. - Cranbury, NJ

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The main objectives of this position is the design and synthesis of compounds (individual or as part of libraries) or process optimization and scale-up synthesis of drug candidates and key intermediates in accordance with approved project protocols. In addition, the employee may supervise other scientific staff and external contract manufacturers. As a medicinal chemist the employee serves as a key contributor to drug discovery programs, frequently designs new or modifies existing experimental procedures or technologies and has an in depth knowledge of not only organic/medicinal chemistry and related drug discovery disciplines (pharmacology, toxicology, pharmacodynamics, etc.) but also their interrelationship to advancing drug candidates. For process optimization and scale-up, the employee will be required to create technology transfer documents to be used by external manufacturers, may be required to review and maintain CMC documents, manufacturing, and batch records, may serve as a coordinator of API supply for multiple development projects and have a good understanding of regulatory requirements.Adherence to good laboratory practice and the maintenance of detailed laboratory notebooks and data records are critical.

PRINCIPAL ACCOUNTABILITIES:
  • Preparation of compounds for submission for biological screening including purification, characterization and assessment of purity, or process optimization and scale-up synthesis of drug candidates and key intermediates for preclinical projects.
  • Upkeep of all necessary notebooks and records related to their work.
  • Contribute to the advancement of drug discovery programs through study design, execution, problem solving and data analysis or coordination of API supply for development teams as required including vendor selection, technology transfer reports, reviewing batch records.
  • Supervise other scientific staff and external vendors as required
Educational Requirements

Ph.D. in organic chemistry with 5+ years relevant experience or MS degree with 10+ years of relevant experience.

Required Experience & Technical Requirements

Technical Requirements
Serves as a key contributor to Drug Discovery or Process Chemistry by applying research that is original or conceptual in nature. Data interpretation reflects a working knowledge of interfacing functions and conclusions reflect in-depth analyses. May be involved in evaluating new target areas to be addressed or may serve as a key contributor during the transition of projects from preclinical and development.Brief Description/Overview:

Purdue Pharma L.P. and its associated U.S. companies are known for pioneering research on the principal cause of human suffering: chronic pain. Headquartered in Stamford, Connecticut, it is one of the fastest-growing pharmaceutical companies in the world today. Purdue Pharma has led the battle against inadequate treatment of pain by developing long-acting pain-control medications that are prescribed by healthcare professionals around the world. As the sponsor of Partners Against Pain, the company provides community outreach and educational programs to encourage the therapeutic alliance of patients, their families, caregivers, and healthcare professionals.

Benefits: Purdue offers a wide range of competitive benefits to all full-time employees. Our benefit package includes a variety of benefit programs to provide for the health, welfare and financial security of our employees and their families.

We are an Equal Opportunity Employer committed to a diverse workforce, M/F/D/V. Corporate standards require pre-employment drug testing and background investigation.

If you are interested in a specific open position, you must apply online by visiting our website at www.purduepharma.com. No hard copy resumes will be considered.

Purdue Pharma L.P. - 17 months ago - save job - block
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