postdoctoral fellow structural biology
National Institute of Neurological Diseases and Stroke, NIH - Bethesda, MD
A postdoctoral position is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak at the National Institute of Neurological Disorders and Stroke. The Roll-Mecak Laboratory is interested in understanding the interplay between microtubules and their regulators and how tubulin post-translational modifications tune the behavior of motors and microtubule associated proteins (see for instance Szyk et al., 2011. Nature Struct. & Molec. Biol. 8(11): 1250-8; Roll-Mecak, A. and Vale, R.D. 2008. Nature, 451(7176):363-7; Roll-Mecak, A. and McNally, F.J. 2010. Curr. Opin. Cell Biol., 22(1):96-103). We use a combination of biochemistry, structural biology, cell biology and single-molecule fluorescence techniques. Thus, a postdoctoral fellow in the lab would have the opportunity to move between these techniques and build upon an already strong background in one of these areas. We value a vibrant and collaborative environment where lab members share ideas, reagents and expertise and want to work on fundamental problems in cytoskeletal biology.

The Roll-Mecak lab is located in the Porter Center for Neuroscience on the NIH main campus in Bethesda. The NIH has a long tradition of research excellence in cytoskeletal biology and offers a stimulating environment for postdoctoral fellows interested in interdisciplinary training in cell biology and biophysics. The research facilities at NIH are outstanding and the lab has state-of-the-art equipment such as crystallization robots, liquid handling systems, TIRF and confocal microscopes. For more information, please visit: http://intra.ninds.nih.gov/rm_lab/
The position will be fully funded by the NIH, and is available immediately. We are looking for candidates who wish to work on mechanistic problems related to the microtubule cytoskeleton and have a strong background in at least two of these areas: molecular biology, protein biochemistry, structural biology, cell biology, imaging or single molecule motor biophysics.
Other details: candidates should have less than 2 years of postdoctoral experience. Please send a CV, a one-page research experience summary, and contact information of three references to Antonina@mail.nih.gov Please write “Postdoctoral application” in the subject header.

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