Postdoctoral positions
University of Texas (UT) Medical School, Health Science Center (HSC) at Houston - Houston, TX

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are available at the Department of Microbiology & Molecular Genetics of the University of Texas-Houston Medical School to study the molecular mechanisms of mitosis and cytokinesis. We use Trypanosoma brucei, a unicellular microbial eukaryote and the causative agent of human sleeping sickness, as a model system to address the fundamental questions of how mitosis and cytokinesis are regulated and coordinated during cell division. The current focus is on the cell cycle regulatory circuits consisting of Aurora B and Polo-like kinases, two novel motor proteins, and SCF and APC /C ubiquitin ligases. In addition, we investigate the assembly, dynamics and function of the mitotic structures such as the mitotic spindle, kinetochores and the cleavage furrow by using a combination of genetics, biochemistry, cell biology, and chemical genetics, and our long-term goal is to elucidate the molecular and cellular basis of cell division as well as to provide novel targets for chemotherapy.

Self-motivated and career-oriented recent Ph.D. graduates with strong background in biochemistry, cell biology and molecular biology are encouraged to apply. Please submit a recent CV, and names and addresses of three references to Dr. Ziyin Li at Ziyin.Li@uth.tmc.edu