Senior Research Associate ~ Spanos Lab with Cancer Biology Research Center
Sanford Health 93 reviews - Sioux Falls, SD

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Full-time position: 80 hours per pay period

The Spanos Lab is with the Cancer Biology Research Center. Squamous cell cancer in the head and neck (HNSCC) provides a fascinating dichotomy because approximately 1/3 of the tumors are caused by HPV and about 2/3 are a result of random mutations. Even though HPV(+) HNSCC presents at a more advanced stage than HPV(-) tumors, the survival is markedly (30-40% at five years) better in patients with HPV(+) HNSCC. Advanced stage HNSCC is often treated with radiation therapy. The Spanos lab has developed an immune competent model of HPV(+) and HPV(-) tonsil cell cancer in mice. The preliminary data shows that clearance of HPV(+) cancers treated with radiation occurs only in the setting of an intact immune response. They hypothesize that HPV(+) cancers are curable due to an immune response that is induced to the tumor cells with radiation therapy. The aim is to improve understanding of immunologic clearance so that novel therapies can be created that would decrease treatment and morbidity and increase survival.

Position summary: Under general direction, performs non-complex to moderately-complex laboratory testing, experiments and analyses following established protocols. Incumbent performs research through experimentation and appropriate literature. Maintain carefully written and stored records about progress and process of research. Responsible for compiling and analyzing data and writing reports. Presents findings at meetings. Responsible for maintenance and inventory of lab equipment and supplies. May manage a laboratory facility including equipment and staff.

Must possess ability to implement experiments in the subject discipline with the ability to trouble shoot issues. Good knowledge of the principles and techniques of the subject discipline required. Possesses ability to run complex pieces of equipment requiring advanced specialized training. Must possess knowledge of modern research methods, data collection and analysis. Must have significant experience in analyzing and evaluating data. Ability to work collaboratively with a research group or team.

When students are providing patient care, treatment, and/or services as a part of their training, any/all employees may be asked to supervise the students.

Required Skills

Bachelor's degree in a clinical, health, or life science field with at least seven years of related experience. Prefer Master's degree with five years related experience. Management experience is highly recommended.

Required Experience

About this company
93 reviews
Sanford Health is an integrated health system headquartered in the Dakotas. It is one of the largest health systems in the nation with 43...