Seeking a talented, highly motivated individual to join Biogen Idec's growing Chemical Process R&D group. The individual will independently design experiments, conduct laboratory research and establish an understanding of parameters that control API crystallization processes. The individual will lead the particle design and engineering process in collaboration with project chemists, analytical chemists and drug formulators. The goals of these matrix teams are to discover and deliver robust crystallization processes to produce crystals with desired purity and physical properties. The individual will be responsible for the technology transfer of laboratory scale experiments to commercial scale processes under current Good Manufacturing Process guidelines. The preparation of development reports and regulatory filings for drug candidates following Quality by Design principles is also expected. In addition, the individual is expected to actively bring in new thinking and technology that contribute to the Chemical Process R&D group through innovation and collaborations with both academic and external research institutions.
Biopharmaceutical Sciences (MFG)
The ideal candidate will have in-depth knowledge of crystallization processes, particle characterization, organic chemistry and a working knowledge with analytical instruments used for solids and chemical characterizations. Highly desirable is familiarity with in situ measurement technologies such as near/mid IR, Raman spectroscopies, and focused beam reflectance measurement (FBRM). Strong computational skills for modeling of kinetic/rate processes using DynoChem/COMSOL/ASPEN and statistical analysis using JMP/MODDE is also desirable. The candidate must demonstrate a high level of motivation and scientific curiosity along with excellent communication, writing, collaboration, and technical skills. Must have strong, documented scientific background in chemistry or chemical engineering.
1) BS in Chemical Engineering or Chemistry with 6+ years related experience.
2) MS in Chemical Engineering or Chemistry with 4+ years related experience.
3) PhD in Chemical Engineering or Chemistry with related thesis/graduate work.
Biogen Idec - 21 months ago
Biogen Idec (NASDAQ: BIIB) is a global leader in the discovery, development and delivery of innovative therapies to improve the lives of...