Research Laboratory Technician I
Children's Hospital Philadelphia - Philadelphia, PA

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Bachelor’s degree in Genetics, Biochemistry, Molecular Biology, or equivalent combination of education and experience. Experience in a biology research lab and work with laboratory mice is desired.

  • Knowledge of Molecular Genetics
  • Knowledge of laboratory procedures
  • Communication skills
  • Comfortable working with mice on a daily basis
  • Must be motivated and have assiduous attention to detail, especially in record keeping
  • Diligent efficient, intelligent and highly motivated
  • Lifting, stooping, walking, standing, and carrying materials throughout the laboratory
  • Limited requirement to lift loads up to 20 pounds and exert force up to 20 pounds
  • Sitting and typing on computer terminal
All CHOP employees who work in a patient building or who provide patient care/work with human subjects in clinical trials are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Job Description:
The Children's Hospital of Philadelphia Research Institute is world-renowned, leading research breakthroughs and medical innovations for more than 80 years. The Institute continues its dedication to translating innovative research findings to outstanding patient care. This commitment to excellence will move the CHOP Research Institute from a world-class research institute to the undisputed leader in improving the health of children. Research today at Children's Hospital reflects the institution's commitment to improve child health and concentrates on basic, translational and clinical research on issues of importance and relevance to child health.

With more than 425 investigators and a research staff in the thousands, the Children's Hospital of Philadelphia Research Institute continues its groundbreaking research on diabetes, neonatal seizures, childhood cancer, hemophilia, pediatric heart disease, cystic fibrosis, nutrition disorders, hypercholesterolemia, mental retardation, AIDS, sickle cell disease and numerous other diseases and disorders that affect children. Among its distinguished investigators are seven members of the Institute of Medicine, two investigators of the Howard Hughes Medical Institute, Pew Scholars in Biomedical Sciences, and NIH Merit Scholars.

The Center for Mitochondrial and Epigenomic Medicine is seeking a Research Technician I to manage breeding a colony of genetically modified mice within a large transgenic mouse program. This includes mouse husbandry and maintenance of mouse colonies, as well as routine molecular biology laboratory duties (PCR, etc). This position interacts with staff and researchers as well as students and faculty members. The research supported by this position will involve the use of the mouse as a model system to study the role of bio-energetic defects and epigenetic alterations. The successful candidate will have a Bachelor’s degree in Genetics, Biochemistry, Molecular Biology, or equivalent combination of education and experience. Experience in a biology research lab and work with laboratory mice is desired.

Duties include setting up breeding pairs, weaning, checking plugs, health checks and phenotypic analysis, taking biopsies, record keeping, and coordinating with the animal facility for proper maintenance of mouse husbandry. Routine Molecular Biology will include extraction of genomic DNA from mouse tissue biopsies, molecular genotyping of transgenic animals by PCR, keeping laboratory records and databases, prepare laboratory stock solutions, ordering reagents, and occasional guidance of student helpers.

Mandatory Requirements:
  • Child Abuse Clearances
  • FBI Fingerprint Clearance
  • Drug Screening

About this company
The Children's Hospital of Philadelphia (CHOP) is the nation's first hospital devoted exclusively to the care of children. Since our start...