The University of Iowa - Iowa City, IA

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Percent Time: 100% Type of Position Regular: A position which is considered essential for the effective long-term operation of the university. Persons appointed to this position will receive the privileges and benefits associated with regular employment status. Duties:
Participate in the preparation, maintenance, quality control and distribution of the hybridoma/monoclonal antibody collection of the Developmental Studies Hybridoma Bank (DSHB), a self-supporting National Resource of the NIH providing monoclonal antibodies and products at cost to researchers world-wide. Participate in the basic research of the Institute for Monoclonal Antibody Technologies using monoclonal antibodies in cancer research.

  • Maintain the DSHB collection of over 1,500 hybridoma cell lines through cell culturing, screens, ELISAS and western blots; maintain required records. With the senior research associate, design and implement product quality controls. Requires occasional evening and frequent weekend time commitments.
  • Perform quality control testing of monoclonal antibodies using standard protocols including, but not limited to, immunostaining, western blotting, ELISA and antibody conjugation.
  • Perform basic and complex procedures to maintain and produce the cell product inventory for the DSHB; monitor inventory and make decisions independently regarding the production of new stocks.
  • Direct lab technicians and coordinate the daily fulfillment of DSHB orders for hybridoma cells and cell products.
  • Design experimental protocols and techniques to perform independent research projects on cell culturing and screening of cancer cell lines for cancer stem cell markers. Present findings to lab research collaborators.
  • Collaborate with the research associate, to develop new production methods and products; participate in the selection, procurement and implementation of new equipment. Monitor laboratory equipment and perform quality control testing.
  • Train lab personnel and grad students on cell maintenance techniques and lab preparation protocols.
  • Perform and present cost analyses for new product methods and special service contracts.
  • Read and review articles and critically analyze literature to investigate new production methods and develop new research techniques.
  • Provide technical support to customer inquiries by phone and email.
  • Establish and maintain standards of collaborative interaction among peers and employees that is characterized by respect, honesty and service; assure that all unit members are held to similar standards and ethics; constructively manages conflict.
  • Manage the talents, strengths and behaviors of each individual in a diverse work group while providing each employee with the opportunity to contribute to the goals of the unit. Work to assure that all supervisors and employees are respected and treated consistent with University policies in regard to equal employment opportunity and diversity.
  • Inspire and motivate others to high performance by exercising strong
stewardship of University resources, setting expectations, measuring success

through individual performance evaluations, and driving organizational results.

  • Identify opportunities for and creates development plans that encourage employees to attend to the growth of their personal and professional capacity; engage self and staff in collective reflection of the University’s greater role in society.
Education Required:
  • A Bachelor’s degree in Biology or an equivalent combination of related education and progressively responsible work experience is required.. Experience Required:
  • Related experience of the level typically associated with 3-5 years of related research experience is required.
  • Extensive experience in hybridoma cell culturing techniques is required.
  • Ability to conduct an independent research project using monoclonal antibody technology, as well as the ability to collect and analyze data is required.
  • Ability to work evenings and weekends as required setting up laboratory experiments or handling emergency situations is required.
  • Proficient internet and computer skills; ability to learn new production/inventory software is required.
  • Excellent written and verbal communication skills with colleagues and the research public are required.
  • Demonstrated ability to perform accurate work, meet deadlines and accomplish goals is required.
Desirable Qualifications:
  • A Master’s degree in Biology is desirable.
  • Supervisory experience is desirable.

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