Assoc. Principal Scientist Biotech-PHA001090
Merck is a global health care leader with a diversified portfolio of prescription medicines, vaccines and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company - one that is ready to help create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you'll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
The successful candidate will be responsible for developing formulations for insulin type of molecules and other therapeutic proteins in support of programs at various stages of development. Primary duties to support both early and late stage development candidates will include screening and developing formulations, clinical manufacturing process, technology transfer to pilot plants and regulatory filing. The candidate will provide oversight to use innovative approaches to design robust formulations, high throughput screening and manufacturing processes suitable for sterile dosage forms. Active management and coaching of scientists, participation on formulation development teams and interfacing with cross-functional areas to drive project milestones will be required. The candidate should have strong communication skills, good interpersonal skills, ability to multi-task, publication track record and a strong desire to learn, contribute and collaborate. Protein formulation development, biophysical characterization, scale-up and regulatory filing experience is required. The candidate will provide technical/scientific leadership within department and serves as a department representative on cross-functional teams and professional affiliations. Prior experience in leading a group and technical teams is essential.
Education Minimum Requirement:
Required Experience and Skills:
- M.S with a minimum of 10 years of relevant experience or a Ph.D. in Pharmaceutics, Pharmaceutical Sciences, Biochemistry, Chemical Engineering, Chemistry or a related field.
Desired Experience and Skills:
- Experience with protein formulation development.
- Formulation and biophysical analysis of insulins, design of experiments, clinical process development of drug product, project management, regulatory document preparation and filing.
Our employees are the key to our company's success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Merck's benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. merck.com/careers to create a profile and your resume for requisition # PHA001090.
- Preformulation of proteins, formulation of antibody-drug conjugates, drug delivery, bioassay.
- Experience with protein/peptide crystallization.
- Experience with Waters and Agilent HPLC instruments, Empower and ChemStation.
- Working knowledge of biophysical techniques (e.g., UV, DLS, DSC, Fluorescence, viscosity, particle sizing)
Merck is an equal opportunity employer, M/F/D/V - proudly embracing diversity in all of its manifestations.
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Job: Biologics, Vaccines, Analytical Formulat
Job Title : Prin. Scientist, Bio & Vacc Formul
Primary Location: NA-US-NJ-Summit
Employee Status: Regular
Travel: Yes, 5 % of the Time
Number of Openings: 1
Merck makes medicines for a number of maladies, from stuffy noses and asthma to hypertension and arthritis. The...