DOE Joint Genome Institute (JGI) in Walnut Creek, CA (a division of the
Lawrence Berkeley National Lab) has an exciting research opportunity available
for an experienced Bioinformaticist. Will work within a small scientific team as part of the
Microbial Genome and Metagenome program and serve as a Bioinformaticist Research Scientist and
perform research relevant to the analysis of single cell genomes. Strong
emphasis will be placed on the development of new bioinformatics tools and
approaches for analyzing and visualizing single cell data sets
including co-assemblies of single cell and environmental data. Will distribute results to the scientific community by
publication, scientific presentations, and over the web and collaborate with a team of
software developers to implement bioinformatics tools as part of the JGI QC
pipeline and Integrated Microbial Genomes System (IMG). Position will report to
the Microbial Genomics Program lead.
Design and implement gene and genome
analysis methods, develop and apply computational algorithms for the
characterization and comparison of large-scale DNA sequence datasets (single
cell genomes, metagenomes) to study the evolution of genes and genomes and
their relationship to organismal complexity and diversity.
Devise and perform tests to assess the
quality of input and output data and troubleshoot moderately complex
systems and data analysis issues.
Compare different assembly strategies
and sequencing platforms and summarize the findings concisely.
Contribute to the development of
visualization tools for complex biological data and novel algorithms to
solve bioinformatics problems relating to single cell datasets.
In collaboration with scientific programmers
and software developers in at the JGI, work on pipeline development for
microbial single cell genome data QC and analysis, to automate some of the
commonly used data processing steps.
Interact with peers within and outside
of the JGI to ensure efficient communication and completion of analysis
Store and organize results for
presentation and viewing by JGI collaborators and the wider scientific
Publish in peer review journals and deliver
scientific presentations at scientific meetings
Attend and present status reports at
Keep and maintain accurate and detailed
records of all research and experiments performed.
meetings and present technical status reports and scientific results.
Key Success Factors
Ph.D. in Bioinformatics or a related field.
Familiarity with molecular biology, comparative genomics,
metagenomics, and microbial ecology.
Experience in biological data analysis using programming languages
such as Perl, C/C++, Java, or equivalent.
Expertise in developing computational algorithms and building and
using computer tools and databases for bioinformatics research and
Broad understanding of bioinformatics
tools used for genome and metagenome analysis (i.e., assembly, binning,
gene calling, etc.) and gene function prediction (i.e. sequence alignment,
database search, etc.).
Experience with statistical data analysis using R, visualization of
(comparative) genomics data and phylogenetic analysis.
Experience with HPC environments/distributed computing such as Sun
Grid Engine (SGE) or equivalent.
Ability to document and summarize research results for presentation
and publications; must have a strong record of publications in
Strong analytical and organizational skills.
Excellent interpersonal, oral, and written communication skills.
Ability to work independently as well as part of a diverse team.
Proficient computer skills, including experience using UNIX/Linux,
Mac and/or PC operating systems.
This is a two-year
career-track term appointment that may be renewed to a maximum of five years
and that may be converted to a career position based upon satisfactory job
performance, continuing availability of funds, and ongoing operational needs. The
work schedule may include off-hours and/or weekends. Work will be performed at the DOE Joint
Genome Institute (JGI) located in Walnut Creek, CA. Detailed information about the Joint Genome
Institute program can be found at:
How to Apply
To apply, please click "apply online" and follow the application
Berkeley Lab is an affirmative action/equal opportunity
employer committed to the development of a diverse workforce.
Lawrence Berkeley National Laboratory - 21 months ago
LBNL is a U.S. Department of Energy national laboratory located in Berkeley, California. It conducts unclassified scientific research and is...