Bioinformatics Engineer II
Dana-Farber Cancer Institute - Boston, MA

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Job Summary

Located in Boston, Dana Farber Cancer Institute brings together world-renowned clinicians, innovative researchers, and dedicated professionals as allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Belfer Institute is dedicated to translating basic discoveries into new effective therapies for cancer. The integration of basic research and drug discovery programs at the Belfer Institute provides a unique opportunity to convert critical basic discoveries in the laboratory into novel targeted therapies to improve the lives of cancer patients. This highly integrated goal-oriented organization represents a new academic construct that provides an unprecedented opportunity to change the way anti-cancer therapeutics are discovered and developed. For more information please visit: . The Belfer Institute is fully integrated with the Department of Medical Oncology at the Dana-Farber Cancer Institute and the Cancer Genome Analysis platform at the Broad Institute where genomic discoveries have led to the development of successful therapeutics in a number of disease areas in the past decade.

As part of our scientific team, we are seeking an outstanding scientist with significant experience in bioinformatics to assist in leading a bioinformatics group to identify new targets and biomarkers, delineate mechanisms of resistance, and support the discovery and development of novel oncology therapeutics. A particular emphasis will be in lung cancer. This individual will work closely with diverse partners from industry and academia to deliver high-quality results from within a premier academic setting.

Primary duties and responsibilities will include:
  • Work with investigators at the Belfer and Dana-Farber in the design and analysis of bioinformatics projects
  • Act as a scientific leader in corporate & academic collaborations and as a liason to oncology bioinformatics & sequencing communities at Dana-Farber and the Broad Institute
  • Lead efforts to analyze many different high-dimensional datasets from both internal and external sources
  • Identify novel targets, biomarkers, mechanisms of resistance, and effective therapeutic combinations through analysis of bioinformatic data.
  • Design and implement approaches to solve complex computational problems as they relate to interpreting biological data.
  • Act as key technical resource for researchers seeking assistance with development and implementation of computational, mathematical and statistical methods and analysis.
  • Effectively communicate data and results to stakeholders on project teams.

Job Qualifications
  • Ph.D. plus at least 3 years of experience in the field of oncology, with post-doctoral experience as a plus.
  • Experience in analyzing oncogenomic datasets is essential
  • Strong statistical skills including proficiency with R and/or Matlab
  • Independent, self-motivated and innovative.
  • Ability to excel in a goal-oriented, multifaceted and fast-moving team environment.
  • Outstanding communication, organizational and leadership skills


This is a full time, 40 hour per week position.

Dana-Farber Cancer Institute is an Affirmation Action/Equal Opportunity Employer - committed to diversity and inclusion in our workforce.

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