The University of Washington (UW) is proud to be one of the nation’s premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement, artistic pursuits, and natural beauty.
The Department of Bioengineering is inventing the future of medicine. UW faculty and students bridge the disciplines of medicine and engineering to drive healthcare forward for those in remote parts of the world and here at home. Students, SCIENTISTs, engineers, and physicians come together at UW Bioengineering to develop innovative and cost-effective approaches to improve health care. Our interdisciplinary teams conduct groundbreaking research spanning five comprehensive research themes: 1) Biomaterials and Regenerative Medicine, 2) Instrumentation, Imaging, and Image-guided therapy, 3) Molecular and Cellular Engineering, 4) Systems and Quantitative biology, and 5) Technology for Expanding Access to Healthcare.
UW Bioengineering is a recognized leader in using education and research to encourage biomedical invention. The department is successful in translating research discoveries to real-world applications through multi-partner initiatives. Our faculty and alumni have launched numerous successful start-up companies and regularly license technology to industry partners, fueling our economy and transforming health care.
The Department is unique at the University of Washington in that it is administered through both the School of Medicine and the College of Engineering. The Department of Bioengineering is located in the W.H. Foege Building, at the corner of 15th and Pacific. The majority of the staff assignments in the department involve interaction with core faculty, adjunct faculty, staff and post-docs, as well as graduate and undergraduate students.
The Department of Bioengineering has an outstanding opportunity for a Research SCIENTIST Engineer 3. This position will support a Research Project to develop a multiplexable autonomous disposable nucleic acid amplification test (MAD NAAT) for use in limited-resource settings. The overall goal of the project is to create an instrument-free fully disposable diagnostic platform for the detection of nucleic acids that is designed for use in limited-resource settings. The diagnostic platform will be so simple to operate that it would be appropriate for untrained users. This multiplexable autonomous disposable nucleic acid amplification test (MAD NAAT) platform will perform all steps from sample to result and archive samples for subsequent laboratory analysis.
The specific responsibilities of this position is as follows:
For detailed information on Benefits for this position click here.
- Primarily responsible for the sample preparation (cell lysis and NA purification) of a wide variety of bacteria compatible with the
- Integrated MRSA MAD NAAT device platform.
- Performs experiments in chemical and potentially mechanical lysis by developing protocols modified from commercial kits and literature examples for gram negative targets, gram positive targets, mycobacterium, and potentially other bacterial targets.
- Responsible for any bacterial colony growth required for sample preparation testing, including potential use of Biosafety Level 2 facilities.
- Uses tools including quantitative PCR, isothermal amplification methods, and gel electrophoresis to verify lysis and purification results.
- Works closely with graduate students to develop the optimal lysing scheme for this broad sample of bacteria with minimal managerial oversight.
- Maintaining a laboratory notebook for all research activities according to established UW rules.
- Participating in (weekly) technical meetings to discuss progress and plans with the rest of the technical team.
- Meeting with the manager no less frequently than monthly to discuss progress on the project
- Publication of work
- Advising undergraduates and graduate students as necessary for carrying out the duties noted above
- Collaboration with other personnel on 2DPN diagnostics projects carried out within the Yager/Lutz/Fu group at UW
- Making presentations at Yager/Lutz/Fu group meetings as fits into a group-wide rotation
- Writing and submitting to supervisor short but comprehensive monthly reports summarizing your research activities no later than the 10th day of the month subsequent to that on which the report is based
A Master's degree in Mechanical Engineering, Bioengineering, Electrical Engineering or related fields AND 3-5 years of relevant education experience
(Further equivalent experience be substituted for degree requirement)
Knowledge, skills, abilities, and other:
Equivalent education/experience will substitute for all minimum qualifications except where there are legal requirements such as license/certification/registration.
- Strong engineering background
- Ability to design high-quality experiments and draw appropriate conclusions
- Ability to self-direct and meet deadlines
- Ability to communicate effectively and work cooperatively with colleagues
- Ability to produce high-quality results and to write manuscripts
- Established record of optimizing a multi-part design by investigating multiple improvements and trade-offs
- Experience with fabrication (metal working, wood, 3D printing, mixed materials, etc)
- Strong communications and verbal skills
Condition of Employment:Application Process:
- Experience with Microsoft Project
- Experience working on large teams
- Experience in Design for manufacturing
- 3D modeling (ideally SolidWorks)
- Some wet chemistry experience
Part of the application process for this position includes completing an on-line cover letter assessment as well as the Employment Eligibility Assessment to obtain additional information that will be used in the evaluation process. The assessment(s) will appear on your screen for you to complete as soon as you select "Apply to this Position" on this job announcement. Once you begin the assessment, it must be completed at that time. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until the assessment is complete.
A satisfactory result from a criminal background check may be required prior to hire.
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