Research Associate/Senior Research Associate, Protein Mass Spectrometry
Sutro Biopharma, Inc. - South San Francisco, CA

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Sutro Biopharma, located in South San Francisco, is developing a new generation of antibody drug conjugate therapeutics and bifunctional antibody-based therapeutics for targeted cancer therapies. These therapeutics will significantly extend the clinical impact of current oncology therapeutic approaches and are beyond what can be envisioned with current cell-based expression technologies. Sutro's biochemical synthesis technology, which underpins these therapeutics, allows the rapid and systematic exploration of many protein drug variants to identify drug candidates. Once these product candidates are identified, production can be rapidly and predictably scaled up to commercial levels. Sutro has established a Good Manufacturing Practice (cGMP) facility for the production of clinical supplies of materials using its biochemical protein synthesis platform. Sutro Biopharma is collaborating with pharmaceutical and biotech companies in the discovery and development of novel protein therapeutics.

Sutro Biopharma, Inc. is looking for energetic and talented individuals to join its multidisciplinary research and development team. You will be working to maximize our technology and internal and collaborative product development initiatives in a fast paced environment.

We are seeking a Research Associate/Sr. Research Associate to join our Protein Analytical Chemistry group to support R&D of monoclonal antibodies and antibody drug conjugates using state of the art chromatographic and mass spectrometry techniques.

Responsibilities:
The candidate we are seeking will work with scientists on developing and running HPLC and LC/MS based proteomic/metabolomic profiling assays and protein characterization assays. The candidate will be responsible for routine sample processing, sample analysis, data analysis and presentation of results in internal/external meetings. Job will also include developing and running assays to monitor protein stability (for example, oxidation and deamidation) by HPLC and LC/MS. Candidate with experience in operation and maintenance of Waters and Agilent LC/MS systems will be given preference. Ideal candidate will have experience in drug discovery/development/QC environment and possess a strong work ethic and communication skills.