Research Associate, Process Development
G-CON, LLC - College Station, TX

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DESCRIPTION

Performs recombinant protein/monoclonal antibody purification and process development for cGMP manufacturing

DUTIES

Assisting in developing and executing protein extraction and purification protocols using Design Of Experiments;

Performing protein analysis such as SDS-PAGE, concentration determination, ELISA, Western Blot, and HPLC;

Performing protein purification using column chromatography at both small and large scales using AKTA workstations such as Avant, Pilot, and Process;

Performing various kinds of filtration such as depth filtration, nanofiltration, microfiltration, and ultrafiltration/diafiltration;

Assisting in purification process transfer to cGMP manufacturing;

Preparing technical summary and reports and presenting data to team meetings;

Any other tasks as assigned.

QUALIFICATIONS

BS/MS in biology, chemistry, biochemistry or related fields;

Minimum of 2 year's relevant research and development experiences in protein purification and analysis;

Experienced with operating AKTA line of chromatography workstations such as Explorer, Avant, and Pilot;

Experienced with various chromatography based on affinity, ion exchange, size exclusion, and hydrophobicity interaction;

Experienced with filtration techniques particularly ultrafiltration/diafiltration;

Good working knowledge of basic protein chemistry;

Good communication and presentation skills;

Experiences with DOE and cGMP operation are desired but no required;

Good aptitude in generalized software operation and data management;

Good problem-solving and multi-tasking ability;

Able to work independently with some supervision.
Assisting in developing and executing protein extraction and purification protocols using Design Of Experiments;

Performing protein analysis such as SDS-PAGE, concentration determination, ELISA, Western Blot, and HPLC;

Performing protein purification using column chromatography at both small and large scales using AKTA workstations such as Avant, Pilot, and Process;

Performing various kinds of filtration such as depth filtration, nanofiltration, microfiltration, and ultrafiltration/diafiltration;

Assisting in purification process transfer to cGMP manufacturing;

Preparing technical summary and reports and presenting data to team meetings;

Any other tasks as assigned.

About this company
The Company maintains an integrated product team of engineers with bioprocess development, mechanical-electrical, and heating, ventilation,...