Scientist - Metabolite Profiling and Indentification
Covance - Madison, WI

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Job Posting

Scientist – Metabolite Profiling and Identification


We are looking to add a Staff Scientist – Metabolite ID and Profiling to our Drug Metabolism team. In this role, you will perform day-to-day technical management of studies. Other job duties would include the following:
  • Responsible for the design, conduct and reporting of studies to meet scientific, regulatory and client requirements.
    Review technical validity of projects and results
    Maintain positive control over timing and scheduling issues related to the study process.
    Identification of drug metabolites using liquid chromatography-tandem mass spectrometry, NMR, and other analytical methodologies.
    Quantitative analysis using LC-MS/MS.
    Implements new techniques and instrumentation to improve technical operations.
    Accepts leadership role in troubleshooting and solving challenging bioanalytical and biotransformation problems.
    Prepares scientific reports that document the analytical results and interpretation for the identification of drug metabolites.
    Performs scientific mentoring activities (e.g.; training study specific techniques, assisting with complex analytical work/problem solving, and presenting technique seminars).
    Assesses interest and feasibility of research projects requiring a high degree of creativity and technical organization.
    Conducts both fundamental and general application studies in the areas of bioanalytical chemistry and biotransformation.
    Authors scientific papers, which are published in peer reviewed journals, and presented in scientific meetings.

With two state-of-the-art metabolism laboratories in Madison, Wisconsin, and Harrogate, UK, Covance has helped hundreds of pharmaceutical and biotechnology companies select compounds to progress into development. Covance provides a comprehensive range of ADME services to support drug discovery and development programs. At Covance, you can make a difference by helping to deliver life-saving and life-enhancing medicines to people around the world. Our commitment to this mission has resulted in Covance’s impressive history of company stability and growth. We’ve achieved these results by fostering a work environment that encourages, develops and leverages our team’s capabilities.

Bachelors of Science (BS) degree in science required.
PhD degree desired (additional experience not required with a PhD).

Knowledge of GLP and regulatory guidelines.
Proficiency in project management skills.
Ability to conduct literature review.
Skilled in data interpretation and report writing for studies.
Familiar with the use of standard laboratory equipment and analytical instrumentation, including GC/MS, HPLC and LC/MS.
Skilled in customer service communication.

Required Experience/Skills for the Scientist – Metabolite Profiling and Identification includes:

  • Experience in structural characterization and identification of drug metabolites using LC/MS/MS.
  • Extensive experience and knowledge of drug biotransformation and identification of drug metabolites.
  • Experience in technical client management.
  • Skilled in customer service communication
  • Highly skilled in conducting research, data interpretation and writing reports.
  • Proven track record of analytical method development (HPLC, LC-MS, LC-MS/MS).
  • Effective oral and written communication skills.
  • Experience and knowledge of Good Laboratory Practices (GLP) is a plus.

  • This position is located in Madison, WI. Madison has a vibrant economy with plentiful jobs, superb health care, and a low crime rate. Due to the University of WI, Wisconsin's state government and Madison's lakes, its residents enjoy many nationally recognized festivals and leisure activities. In the past decade, Madison has placed in the top ranks among US cities in many categories including the Best City in America, Best Place for Business, most “Kid Friendly” cities and Best Cities for Women. Madison has a very strong public school system with Wisconsin's graduates consistently ranking among the best in ACT college entrance examination scores.

    An additional benefit of living in this area is that Chicago is only 2 hours away by car and Milwaukee only an hour and a half. At the same time, a short half hour drive can put you well into open space and wildlife. Madison's residents have come to appreciate that this area holds something of interest for nearly everyone.

    Covance is a leading supplier of drug development services to the biotechnology and pharmaceutical industries. We partner with innovative companies, offering valuable services in all phases of the drug development process as well as analytical and commercial impact services. As an integral part of these partnerships, our employees make a difference in the lives of millions.

    Before drugs, chemicals, or foods can be sold, they must be evaluated for safety and effectiveness. Covance provides international testing services to clients in the pharmaceutical, food, biotechnology and chemical services industries

    Because of our passion and drive, Covance attracts the kind of people whose contribution has resulted in our exceptional growth. Once a part of our talented team, our employees stay at Covance to work in an environment that encourages career development, allows them to work alongside respected colleagues on challenging projects and provides a diverse global culture.

    There is no better time to join us!

    EEO Employer
    Covance is committed to diversity in the workplace and is an equal opportunity employer. (M/F/D/V). Your confidentiality and privacy are important to us.

    Covance - 2 years ago - save job
    About this company
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    Covance Inc. is a drug development services company providing a range of early-stage and late-stage product development services on a...