Senior Research Technician - The Genome Institute - 24211
Washington University in St. Louis - St. Louis, MO

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Job Type/Schedule

This position is full-time and works approximately 40 hours per week.

Department Name/Job Location

This position is in The Genome Institute. This position is for the Medical School Campus.

Essential Functions

The applicant is expected to independently perform complex research studies, experiments and assays.

The laboratory performs research on the human microbiome, microbial genomics and genetics, and human genetics as well as collaborates with other research groups throughout the Washington University community and at other institutions. The focus is on research and development projects. The laboratory is also engaged in testing new instruments as R&D activities and then introducing such new methods into the laboratory environment.

The laboratory has a number of operations that are necessary preludes for data production in which the candidate will be expected to contribute. These include preparation of samples for multiplex sequencing of 16S rRNA genes, preparation for shotgun sequencing from low input DNA amounts, preparation of RNA and cDNA for virome and transcription analysis, operation of an Eppendorf robot for DNA preparation from bacterial samples, and manual DNA preparation from bacterial cultures. A number of computational and analysis activities are necessary in support of these laboratory methods to assure the quality of the data produced. Additional analytical and computer support is required for various instrument systems, often requiring knowledge of Unix/Linux operating systems.

The laboratory has instrumentation that is unique to The Genome Institute such as the OpGen Argus system that generates physical maps from genomic DNA and the Biolog metabolite analyzer. The applicant is expected to master new instrumentation and help train others in their use.

1. Performs complex analysis/projects according to research protocols, explaining methods and procedures to other technicians. Helps create and validate new experimental protocols as needed.

2. Performs testing of new methods and new instruments for introduction into the laboratory environment.

3. Has experience in formal presentation of experimental results.

4. Provides for data entry and current data files on research projects. Monitors data to ensure consistent quality.

5. May perform in depth statistical analysis of data.

6. Manage lab environmental & radiation safety compliance. Maintains required documentation on laboratory and specimen conditions.

7. Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.

8. Assists in the training and development of technicians, acting as a group leader.

9. Prepares Whole Genome Shotgun Libraries for genomic sequencing.

10. Prepares complex media required in Microbial Lab and trains other technicians in this process.

Required Qualifications

MINIMUM EDUCATION & EXPERIENCE: Master’s degree with 2 years of experience in a laboratory setting or equivalent combination of education and experience equaling 7 years required.

CRITICAL SKILLS/EXPERTISE: Demonstrated ability to work independently and communicate with laboratory staff and investigators. Ability to maintain complete and organized records/reports. Working knowledge of computer software and general lab equipment.

Preferred Qualifications

  • Broad understanding of concepts involved in bacterial and human genetics and familiarity with multiple modern molecular biology techniques and their use in research projects strongly preferred.
  • Experience in formal presentation of experimental results.
  • Demonstrated ability to learn new experimental techniques quickly in a research environment and to multitask.
  • Willingness to work with others in a team is strongly preferred.
  • Experience with computer–based sample tracking procedures.
Salary Range

The hiring range for this position is $34,008 to $45,905 annually.

Department Summary

The Genome Institute is one of only three NIH-funded large-scale genome centers in the United States, The Genome Institute at Washington University is a leader in genomics research as it applies to the study of biology, human disease and the field of personalized medicine. Founded in 1993, The Genome Institute focuses on cancer genomics, the genomics of heritable diseases, microbial and pathogen genomics, as well as novel sequencing and evolutionary genomics.

Our mission is to help improve the human condition by producing, studying, and interpreting high-quality genome-based data that drives biological discoveries that range from the bench to the hospital bedside. We value the open sharing of information and ideas and encourage collaboration while also engaging the next generation of scientists through educational outreach efforts.

Our group is dynamic and interactive, and most projects require close teamwork among senior scientists, postdocs, and staff, promoting excellent opportunities to acquire new skills. It is an exciting era to be a scientist, and we now have the ability to use vast whole genome profiling techniques to address biological questions that were previously unanswerable. If you would like to join this team please apply for this position today.


This position is eligible for full-time benefits. Please visit our website at to view a summary of benefits.

Applicant Special Instructions

Works in laboratory environment with potential exposure to biological, chemical and radioactive hazards. Must be physically able to wear protective equipment.

EOE Statement

Washington University in St. Louis is an equal opportunity, affirmative action employer and encourages applications from women, ethnic minorities, veterans, and individuals with disabilities.

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