Two Postdoctoral Fellow Positions: Gene Regulation in Breast Cancer/Stem Cell Biology
H. Lee Moffitt Cancer Center & Research Institute - Cincinnati, OH

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The Zhang Laboratory at the Department of Cancer and Cell Biology at University of Cincinnati is currently expanding and recruiting two Postdoctoral Fellow to study transcriptional and epigenetic regulation of gene expression in breast cancer. The Zhang laboratory focuses on elucidating molecular mechanisms of gene- and tissue- specific transcriptional cofactors [Mol Cell 19:89-100, PNAS (2010) 107: 6765, PNAS (2010) 107:10196, JBC (2011) 286(20): 17746, EMBO J. (2011) 30(12): 2405, Cancer Research (2012) doi: 10.1158/0008-5472.CAN-12-1305] in breast cancer and stem cells determination by using a combination of biochemical, molecular, genomic (RNA-seq, ChIP-seq) as well as mouse genetic (conditional knockout, mutant knockin and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors to overcome the endocrine and chemo- therapeutic resistance of human breast cancer.

The Zhang laboratory is located at the state-of-art Vontz Center for Molecular Studies of the College of Medicine. The Vontz Center is situated in the Medical Center which includes Cincinnati Children’s Hospital Medical Center, College of Medicine, UC Cancer Institute, University Hospital and Barrett Cancer Center. The medical center is a dynamic and collaborative environment research environment through strong partnerships between Children’s Hospital Medical Center and the University of Cincinnati, with total annual NIH funding ranked in the top 30 of the country. Cincinnati is the 27th big city in the United States and is considered as one of most livable city with affordable cost and amicable climate.

Interested candidates must have a Ph.D. and/or M.D. degree with research experience in biochemistry, molecular or cellular biology. Prior experience with animal studies or RNA-seq/ChIP-seq is a plus. Salary is competitive with an attractive benefits package that includes family health insurance, retirement contributions, etc. If interested, please submit a CV and list of contact information for three references to:

Xiaoting Zhang, Ph.D.

Associate Professor

Department of Cancer and Cell Biology

The Vontz Center for Molecular Studies

University of Cincinnati College of Medicine

3125 Eden Avenue

Cincinnati, OH 45267

Office: (513)558-3017

Lab: (513)558-8083

Email: zhangxt ucmail.uc.edu

Website: http://cancerbiology.uc.edu/zhangxt

Lab Homepage: http://homepages.uc.edu/~zhangxt/index.html

All interested applicants could also submit applications to positions number 212UC3840 or 212UC3841 via the UC Jobs website: www.jobsatuc.com.

Contact:
Xiaoting Zhang

Cancer and Cell Biology

University of Cincinnati

Cincinnati, OH 45267

United States

Email: zhangxt ucmail.uc.edu

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The H. Lee Moffitt Cancer Center and Research Institute, founded in 1986, is a National Cancer Institute-designated Comprehensive Cancer...