High-paying nursing jobs in Saint Charles
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 1,141 nursing jobs listed below pay well, with salaries between $44,785 and $109,247 per year. Registered Nurse, Licensed Practical Nurse and Nursing Assistant are among the most popular high-paying roles in Saint Charles, MO.
Job title
Updated Aug 26, 2026
Job title
Saint Charles, MO
Missouri
Job openings (Saint Charles)
Registered Nurse - Critical Care
Saint Charles
$2,184
per week
Missouri
$2,036
per week
Director of Nursing
Saint Charles
$95,564
per year
Missouri
$101,413
per year
Registered Nurse
Saint Charles
$45.47
per hour
Missouri
$40.48
per hour
Licensed Practical Nurse
Saint Charles
$32.15
per hour
Missouri
$32.12
per hour
Nursing Assistant
Saint Charles
$19.83
per hour
Missouri
$18.82
per hour
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
-
Registered Nurse - Critical Care
Review job description
Please refer to the employers job description for complete details.
Critical care RNs provide patient care, monitor vital signs and support medical teams in critical settings. Experience in critical care and clinical skills is essential in this role.
Registered Nurse - Critical Care jobs take 104 days on average from job posting to starting date. Currently, 17% of job openings are part-time roles.
See 39 jobsAverage pay
Saint Charles
$2,184 per weekMissouri
$2,036 per weekSkills
- Critical care experience
- ICU experience
- Hospital experience
- Acute care
- Medication administration
-
Director of Nursing
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Please refer to the employers job description for complete details.
Directors of nursing oversee nursing operations, manage staff and ensure compliance with healthcare standards. Leadership skills, healthcare expertise and strategic planning experience are essential.
Director of Nursing jobs take 27 days on average from job posting to starting date. Currently, 2% of job openings are part-time roles.
See 35 jobsAverage pay
Saint Charles
$95,564 per yearMissouri
$101,413 per yearSkills
- Management
- Nurse management
- Long term care experience
- Leadership
- Supervising experience
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Registered Nurse
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Please refer to the employers job description for complete details.
Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 55 days on average from job posting to starting date. Currently, 23% of job openings are part-time roles.
See 428 jobsAverage pay
Saint Charles
$45.47 per hourMissouri
$40.48 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Licensed Practical Nurse
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Please refer to the employers job description for complete details.
Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
Licensed Practical Nurse jobs take 55 days on average from job posting to starting date. Currently, 31% of job openings are part-time roles.
See 358 jobsAverage pay
Saint Charles
$32.15 per hourMissouri
$32.12 per hourSkills
- Nursing
- Medication administration
- Patient care
- Care plans
- Patient monitoring
-
Nursing Assistant
Review job description
Please refer to the employers job description for complete details.
Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 56 days on average from job posting to starting date. Currently, 42% of job openings are part-time roles.
See 281 jobsAverage pay
Saint Charles
$19.83 per hourMissouri
$18.82 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records