High-paying nursing jobs in Saint Charles
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 1,349 nursing jobs listed below pay well, with salaries between $45,128 and $151,162 per year. Registered Nurse, Licensed Practical Nurse and Nursing Assistant are among the most popular high-paying roles in Saint Charles, MO.
Job title
Updated Oct 17, 2026
Job title
Saint Charles, MO
Missouri
Job openings (Saint Charles)
Nurse Practitioner
Saint Charles
$151,162
per year
Missouri
$126,825
per year
Registered Nurse - Critical Care
Saint Charles
$2,101
per week
Missouri
$2,012
per week
Travel Nurse
Saint Charles
$2,083
per week
Missouri
$2,020
per week
Director of Nursing
Saint Charles
$95,202
per year
Missouri
$102,144
per year
Registered Nurse
Saint Charles
$44.71
per hour
Missouri
$53.44
per hour
Registered Nurse - Home Health
Saint Charles
$86,127
per year
Missouri
$80,759
per year
Nurse
Saint Charles
$38.92
per hour
Missouri
$33.29
per hour
Charge Nurse
Saint Charles
$36.95
per hour
Missouri
$34.44
per hour
Licensed Practical Nurse
Saint Charles
$32.33
per hour
Missouri
$32.27
per hour
Nursing Assistant
Saint Charles
$19.98
per hour
Missouri
$18.96
per hour
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
-
Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 101 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
See 138 jobsAverage pay
Saint Charles
$151,162 per yearMissouri
$126,825 per year -
Registered Nurse - Critical Care
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Please refer to the employers job description for complete details.
Critical care RNs provide patient care, monitor vital signs and support medical teams in critical settings. Experience in critical care and clinical skills is essential in this role.
Registered Nurse - Critical Care jobs take 113 days on average from job posting to starting date. Currently, 18% of job openings are part-time roles.
See 26 jobsAverage pay
Saint Charles
$2,101 per weekMissouri
$2,012 per week -
Travel Nurse
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Please refer to the employers job description for complete details.
Travel Nurses provide healthcare services in various locations, adapt to new environments, and ensure patient care standards. Nursing credential, flexibility, and strong clinical skills are crucial.
Travel Nurse jobs take 47 days on average from job posting to starting date. Currently, 2% of job openings are part-time roles.
See 36 jobsAverage pay
Saint Charles
$2,083 per weekMissouri
$2,020 per week -
Director of Nursing
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Please refer to the employers job description for complete details.
Directors of nursing oversee nursing operations, manage staff and ensure compliance with healthcare standards. Leadership skills, healthcare expertise and strategic planning experience are essential.
Director of Nursing jobs take 27 days on average from job posting to starting date. Currently, 2% of job openings are part-time roles.
See 26 jobsAverage pay
Saint Charles
$95,202 per yearMissouri
$102,144 per year -
Registered Nurse
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Please refer to the employers job description for complete details.
Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 68 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See 415 jobsAverage pay
Saint Charles
$44.71 per hourMissouri
$53.44 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
-
Registered Nurse - Home Health
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Please refer to the employers job description for complete details.
Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 58 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
See 44 jobsAverage pay
Saint Charles
$86,127 per yearMissouri
$80,759 per year -
Nurse
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Please refer to the employers job description for complete details.
Nurses administer patient care, monitor health conditions, and collaborate with healthcare teams. Nursing qualification, empathy, and strong clinical skills are essential.
Nurse jobs take 69 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See 62 jobsAverage pay
Saint Charles
$38.92 per hourMissouri
$33.29 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Medical terminology
-
Charge Nurse
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Please refer to the employers job description for complete details.
Charge nurses lead nursing teams, coordinate patient care and manage staff schedules. Key qualifications include maintaining a registered nurse license, leadership skills and strong clinical expertise.
Charge Nurse jobs take 73 days on average from job posting to starting date. Currently, 15% of job openings are part-time roles.
See 58 jobsAverage pay
Saint Charles
$36.95 per hourMissouri
$34.44 per hourSkills
- Nursing
- Medical documentation
- Medical records
- Physiology knowledge
- Medical terminology
-
Licensed Practical Nurse
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Please refer to the employers job description for complete details.
Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
Licensed Practical Nurse jobs take 59 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
See 341 jobsAverage pay
Saint Charles
$32.33 per hourMissouri
$32.27 per hour -
Nursing Assistant
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Please refer to the employers job description for complete details.
Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
See 203 jobsAverage pay
Saint Charles
$19.98 per hourMissouri
$18.96 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records