High-paying nursing jobs in San Diego
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 766 nursing jobs listed below pay well, with salaries between $23.81 and $116 per hour. Licensed Vocational Nurse, Registered Nurse and Nursing Assistant are among the most popular high-paying roles in San Diego, CA.
Job title
Updated Nov 12, 2026
Job title
San Diego, CA
California
Job openings (San Diego)
Psychiatric-mental Health Nurse Practitioner
San Diego
$116
per hour
California
$76.18
per hour
Nurse Practitioner
San Diego
$81.61
per hour
California
$107
per hour
Registered Nurse - Operating Room
San Diego
$2,825
per week
California
$2,624
per week
Registered Nurse - Emergency Room
San Diego
$2,507
per week
California
$2,295
per week
Registered Nurse - Icu
San Diego
$2,474
per week
California
$2,426
per week
Registered Nurse - Home Health
San Diego
$61.65
per hour
California
$68.18
per hour
Registered Nurse
San Diego
$56.37
per hour
California
$56.13
per hour
Hospice Nurse
San Diego
$54.93
per hour
California
$62.17
per hour
Licensed Vocational Nurse
San Diego
$38.62
per hour
California
$36.34
per hour
Nursing Assistant
San Diego
$23.81
per hour
California
$23.78
per hour
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
-
Psychiatric-mental Health Nurse Practitioner
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Please refer to the employers job description for complete details.
Psychiatric-mental health nurse practitioners diagnose disorders, prescribe treatments and support patients. Advanced nursing expertise, empathetic communication and licensure are essential in this role.
Psychiatric-mental Health Nurse Practitioner jobs take 88 days on average from job posting to starting date. Currently, 58% of job openings offer remote or hybrid positions and 23% of job openings are part-time roles.
See jobsAverage pay
San Diego
$116 per hourCalifornia
$76.18 per hour -
Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 97 days on average from job posting to starting date. Currently, 15% of job openings offer remote or hybrid positions and 20% of job openings are part-time roles.
See jobsAverage pay
San Diego
$81.61 per hourCalifornia
$107 per hour -
Registered Nurse - Operating Room
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Please refer to the employers job description for complete details.
Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 106 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
See jobsAverage pay
San Diego
$2,825 per weekCalifornia
$2,624 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
-
Registered Nurse - Emergency Room
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Please refer to the employers job description for complete details.
ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
Registered Nurse - Emergency Room jobs take 51 days on average from job posting to starting date. Currently, 15% of job openings are part-time roles.
See jobsAverage pay
San Diego
$2,507 per weekCalifornia
$2,295 per weekSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
-
Registered Nurse - Icu
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Please refer to the employers job description for complete details.
ICU Registered Nurses monitor patient vitals, administer medication, and provide critical care support. Expertise in critical patient care, strong clinical judgment, and certifications are key.
Registered Nurse - Icu jobs take 39 days on average from job posting to starting date. Currently, 11% of job openings are part-time roles.
See jobsAverage pay
San Diego
$2,474 per weekCalifornia
$2,426 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- ICU experience
-
Registered Nurse - Home Health
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Please refer to the employers job description for complete details.
Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 56 days on average from job posting to starting date. Currently, 27% of job openings are part-time roles.
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San Diego
$61.65 per hourCalifornia
$68.18 per hour -
Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 65 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See jobsAverage pay
San Diego
$56.37 per hourCalifornia
$56.13 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
-
Hospice Nurse
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Please refer to the employers job description for complete details.
Hospice nurses provide compassionate care to terminally ill patients, managing symptoms and supporting families. Expertise in palliative care, strong emotional resilience and nursing licensure are key qualifications.
Hospice Nurse jobs take 75 days on average from job posting to starting date. Currently, 18% of job openings are part-time roles.
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San Diego
$54.93 per hourCalifornia
$62.17 per hour -
Licensed Vocational Nurse
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Licensed Vocational Nurses provide patient care, administer medications, and document treatments. Clinical knowledge, empathy, and attention to procedural details are critical for ensuring patient well-being.
Licensed Vocational Nurse jobs take 57 days on average from job posting to starting date. Currently, 30% of job openings are part-time roles.
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San Diego
$38.62 per hourCalifornia
$36.34 per hour -
Nursing Assistant
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Please refer to the employers job description for complete details.
Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 42% of job openings are part-time roles.
See jobsAverage pay
San Diego
$23.81 per hourCalifornia
$23.78 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records