High-paying nursing jobs in Santa Ana
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 1,477 nursing jobs listed below pay well, with salaries between $50,616 and $152,506 per year. Licensed Vocational Nurse, Nursing Assistant and Registered Nurse are among the most popular high-paying roles in Santa Ana, CA.
Job title
Updated Nov 08, 2026
Job title
Santa Ana, CA
California
Job openings (Santa Ana)
Labor and Delivery Nurse
Santa Ana
$2,790
per week
California
$2,794
per week
Nurse Practitioner
Santa Ana
$143,933
per year
California
$144,520
per year
Registered Nurse - Operating Room
Santa Ana
$2,533
per week
California
$2,623
per week
Registered Nurse - Home Health
Santa Ana
$61.95
per hour
California
$68.08
per hour
Registered Nurse - Icu
Santa Ana
$57.03
per hour
California
$76.79
per hour
Registered Nurse
Santa Ana
$51.77
per hour
California
$56.06
per hour
Registered Nurse - Telemetry
Santa Ana
$50.35
per hour
California
$52.04
per hour
Licensed Vocational Nurse
Santa Ana
$35.35
per hour
California
$36.34
per hour
Registered Nurse - Emergency Room
Santa Ana
$1,406
per week
California
$2,295
per week
Nursing Assistant
Santa Ana
$22.41
per hour
California
$23.80
per hour
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
-
Labor and Delivery Nurse
Review job description
Please refer to the employers job description for complete details.
Labor and Delivery Nurses provide care during childbirth, monitor fetal development, and support families. Expertise in maternal health, strong communication, and a nursing license are required.
Labor and Delivery Nurse jobs take 34 days on average from job posting to starting date. Currently, 14% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$2,790 per weekCalifornia
$2,794 per week -
Nurse Practitioner
Review job description
Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 98 days on average from job posting to starting date. Currently, 13% of job openings offer remote or hybrid positions and 20% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$143,933 per yearCalifornia
$144,520 per year -
Registered Nurse - Operating Room
Review job description
Please refer to the employers job description for complete details.
Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 113 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$2,533 per weekCalifornia
$2,623 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
-
Registered Nurse - Home Health
Review job description
Please refer to the employers job description for complete details.
Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 58 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$61.95 per hourCalifornia
$68.08 per hour -
Registered Nurse - Icu
Review job description
Please refer to the employers job description for complete details.
ICU Registered Nurses monitor patient vitals, administer medication, and provide critical care support. Expertise in critical patient care, strong clinical judgment, and certifications are key.
Registered Nurse - Icu jobs take 39 days on average from job posting to starting date. Currently, 11% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$57.03 per hourCalifornia
$76.79 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- ICU experience
-
Registered Nurse
Review job description
Please refer to the employers job description for complete details.
Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$51.77 per hourCalifornia
$56.06 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
-
Registered Nurse - Telemetry
Review job description
Please refer to the employers job description for complete details.
Registered Nurses - Telemetry monitor patients, administer medications, and collaborate with healthcare teams. RN licensure, proficiency in telemetry, and critical thinking skills are essential.
Registered Nurse - Telemetry jobs take 20 days on average from job posting to starting date. Currently, 11% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$50.35 per hourCalifornia
$52.04 per hour -
Licensed Vocational Nurse
Review job description
Please refer to the employers job description for complete details.
Licensed Vocational Nurses provide patient care, administer medications, and document treatments. Clinical knowledge, empathy, and attention to procedural details are critical for ensuring patient well-being.
Licensed Vocational Nurse jobs take 56 days on average from job posting to starting date. Currently, 30% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$35.35 per hourCalifornia
$36.34 per hour -
Registered Nurse - Emergency Room
Review job description
Please refer to the employers job description for complete details.
ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
Registered Nurse - Emergency Room jobs take 51 days on average from job posting to starting date. Currently, 15% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$1,406 per weekCalifornia
$2,295 per weekSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
-
Nursing Assistant
Review job description
Please refer to the employers job description for complete details.
Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 42% of job openings are part-time roles.
See jobsAverage pay
Santa Ana
$22.41 per hourCalifornia
$23.80 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records