High-paying nursing jobs in Santa Clara
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 512 nursing jobs listed below pay well, with salaries between $35.30 and $99.40 per hour. Licensed Vocational Nurse, Registered Nurse and Nurse Practitioner are among the most popular high-paying roles in Santa Clara, CA.
Job title
Updated Nov 11, 2026
Job title
Santa Clara, CA
California
Job openings (Santa Clara)
Certified Registered Nurse Anesthetist
Santa Clara
$164
per hour
California
$163
per hour
Senior Nurse
Santa Clara
$248,943
per year
California
$71,698
per year
Senior Clinical Nurse
Santa Clara
$99.40
per hour
California
$86.07
per hour
Family Nurse Practitioner
Santa Clara
$152,283
per year
California
$193,984
per year
Registered Nurse - Home Health
Santa Clara
$137,128
per year
California
$125,876
per year
Registered Nurse II
Santa Clara
$57.62
per hour
California
$72.47
per hour
Registered Nurse
Santa Clara
$49.74
per hour
California
$56.06
per hour
Licensed Vocational Nurse
Santa Clara
$35.30
per hour
California
$36.34
per hour
Nurse Practitioner
Santa Clara
$507
per day
California
$294
per day
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Certified Registered Nurse Anesthetist
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Please refer to the employers job description for complete details.
Certified Registered Nurse Anesthetists administer anesthesia, monitor patients, and collaborate with surgeons. Expertise in anesthesia practices, clinical proficiency, and attention to safety are crucial.
Certified Registered Nurse Anesthetist jobs take 82 days on average from job posting to starting date. Currently, 16% of job openings are part-time roles.
See jobsAverage pay
Santa Clara
$164 per hourCalifornia
$163 per hour -
Senior Nurse
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Please refer to the employers job description for complete details.
Senior nurses lead healthcare teams, manage patient care plans and ensure high-quality clinical standards. Advanced nursing expertise, leadership skills and a commitment to patient care are important.
Senior Nurse jobs take 9 days on average from job posting to starting date. Currently, 20% of job openings are part-time roles.
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Santa Clara
$248,943 per yearCalifornia
$71,698 per year -
Senior Clinical Nurse
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Please refer to the employers job description for complete details.
Senior clinical nurses plan patient care strategies, supervise nursing staff and manage complex cases. Advanced clinical expertise, excellent leadership skills and in-depth knowledge of patient care are essential in this role.
Senior Clinical Nurse jobs take 9 days on average from job posting to starting date. Currently, 30% of job openings are part-time roles.
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Santa Clara
$99.40 per hourCalifornia
$86.07 per hour -
Family Nurse Practitioner
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Please refer to the employers job description for complete details.
Family nurse practitioners provide healthcare across the lifespan, diagnose illnesses, and manage treatments. Certification in family practice, clinical expertise, and patient communication are essential in this role.
Family Nurse Practitioner jobs take 99 days on average from job posting to starting date. Currently, 16% of job openings are part-time roles.
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Santa Clara
$152,283 per yearCalifornia
$193,984 per year -
Registered Nurse - Home Health
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Please refer to the employers job description for complete details.
Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 57 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
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Santa Clara
$137,128 per yearCalifornia
$125,876 per year -
Registered Nurse II
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Please refer to the employers job description for complete details.
Registered nurses provide patient care, administer medications and collaborate with healthcare teams. Nursing expertise, strong communication skills and licensure as a registered nurse are required.
Currently, 20% of job openings are part-time roles.
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Santa Clara
$57.62 per hourCalifornia
$72.47 per hour -
Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Santa Clara
$49.74 per hourCalifornia
$56.06 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Licensed Vocational Nurse
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Please refer to the employers job description for complete details.
Licensed Vocational Nurses provide patient care, administer medications, and document treatments. Clinical knowledge, empathy, and attention to procedural details are critical for ensuring patient well-being.
Licensed Vocational Nurse jobs take 58 days on average from job posting to starting date. Currently, 30% of job openings are part-time roles.
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Santa Clara
$35.30 per hourCalifornia
$36.34 per hour -
Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 97 days on average from job posting to starting date. Currently, 15% of job openings offer remote or hybrid positions and 20% of job openings are part-time roles.
See jobsAverage pay
Santa Clara
$507 per dayCalifornia
$294 per day