High-paying nursing jobs in Santa Clara
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 556 nursing jobs listed below pay well, with salaries between $35.63 and $99.51 per hour. Licensed Vocational Nurse, Registered Nurse and Nurse Practitioner are among the most popular high-paying roles in Santa Clara, CA.
Job title
Updated Oct 31, 2026
Job title
Santa Clara, CA
California
Job openings (Santa Clara)
Senior Clinical Nurse
Santa Clara
$99.51
per hour
California
$86.55
per hour
Nurse Manager
Santa Clara
$205,980
per year
California
$144,632
per year
Nurse Practitioner
Santa Clara
$95.62
per hour
California
$107
per hour
Registered Nurse - Operating Room
Santa Clara
$3,346
per week
California
$2,626
per week
Registered Nurse
Santa Clara
$3,263
per week
California
$2,181
per week
Family Nurse Practitioner
Santa Clara
$141,437
per year
California
$198,033
per year
Registered Nurse - Home Health
Santa Clara
$135,675
per year
California
$125,772
per year
Travel Nurse
Santa Clara
$2,402
per week
California
$2,347
per week
Registered Nurse II
Santa Clara
$57.56
per hour
California
$72.57
per hour
Licensed Vocational Nurse
Santa Clara
$35.63
per hour
California
$36.32
per hour
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
-
Senior Clinical Nurse
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Please refer to the employers job description for complete details.
Senior clinical nurses plan patient care strategies, supervise nursing staff and manage complex cases. Advanced clinical expertise, excellent leadership skills and in-depth knowledge of patient care are essential in this role.
Senior Clinical Nurse jobs take 9 days on average from job posting to starting date. Currently, 27% of job openings are part-time roles.
See jobsAverage pay
Santa Clara
$99.51 per hourCalifornia
$86.55 per hour -
Nurse Manager
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Please refer to the employers job description for complete details.
Nurse Managers supervise nursing staff, develop care standards, and manage department budgets. Key skills include leadership expertise, clinical knowledge, and financial management.
Nurse Manager jobs take 43 days on average from job posting to starting date. Currently, 3% of job openings are part-time roles.
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Santa Clara
$205,980 per yearCalifornia
$144,632 per year -
Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 99 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
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Santa Clara
$95.62 per hourCalifornia
$107 per hour -
Registered Nurse - Operating Room
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Please refer to the employers job description for complete details.
Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 109 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
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Santa Clara
$3,346 per weekCalifornia
$2,626 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
-
Registered Nurse
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Please refer to the employers job description for complete details.
Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Santa Clara
$3,263 per weekCalifornia
$2,181 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
-
Family Nurse Practitioner
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Please refer to the employers job description for complete details.
Family nurse practitioners provide healthcare across the lifespan, diagnose illnesses, and manage treatments. Certification in family practice, clinical expertise, and patient communication are essential in this role.
Family Nurse Practitioner jobs take 103 days on average from job posting to starting date. Currently, 23% of job openings are part-time roles.
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Santa Clara
$141,437 per yearCalifornia
$198,033 per year -
Registered Nurse - Home Health
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Please refer to the employers job description for complete details.
Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 58 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
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Santa Clara
$135,675 per yearCalifornia
$125,772 per year -
Travel Nurse
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Please refer to the employers job description for complete details.
Travel Nurses provide healthcare services in various locations, adapt to new environments, and ensure patient care standards. Nursing credential, flexibility, and strong clinical skills are crucial.
Travel Nurse jobs take 43 days on average from job posting to starting date. Currently, 3% of job openings are part-time roles.
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Santa Clara
$2,402 per weekCalifornia
$2,347 per week -
Registered Nurse II
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Registered nurses provide patient care, administer medications and collaborate with healthcare teams. Nursing expertise, strong communication skills and licensure as a registered nurse are required.
Currently, 20% of job openings are part-time roles.
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Santa Clara
$57.56 per hourCalifornia
$72.57 per hour -
Licensed Vocational Nurse
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Please refer to the employers job description for complete details.
Licensed Vocational Nurses provide patient care, administer medications, and document treatments. Clinical knowledge, empathy, and attention to procedural details are critical for ensuring patient well-being.
Licensed Vocational Nurse jobs take 58 days on average from job posting to starting date. Currently, 29% of job openings are part-time roles.
See jobsAverage pay
Santa Clara
$35.63 per hourCalifornia
$36.32 per hour