High-paying nursing jobs in St. Louis
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 1,684 nursing jobs listed below pay well, with salaries between $19.57 and $99.55 per hour. Registered Nurse, Licensed Practical Nurse and Nursing Assistant are among the most popular high-paying roles in St. Louis, MO.
Job title
Updated Sep 10, 2026Advanced Practice Provider
St. Louis
Missouri
Nurse Practitioner
St. Louis
Missouri
Registered Nurse - Operating Room
St. Louis
Missouri
Registered Nurse
St. Louis
Missouri
Registered Nurse - Medical/Surgical
St. Louis
Missouri
Nursing Supervisor
St. Louis
Missouri
Clinical Nurse
St. Louis
Missouri
Charge Nurse
St. Louis
Missouri
Licensed Practical Nurse
St. Louis
Missouri
Nursing Assistant
St. Louis
Missouri
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Advanced Practice Provider
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Advanced practice providers deliver advanced clinical care, conduct patient assessments and collaborate with physicians to develop treatment plans. They need clinical expertise, knowledge of healthcare protocols and strong communication skills.
Advanced Practice Provider jobs take 58 days on average from job posting to starting date. Currently, 13% of job openings are part-time roles.
See 42 jobsAverage pay
St. Louis
$99.55 per hourMissouri
$60.78 per hourSkills
- Advanced practice provider
- Patient care
- Primary care
- Acute care
- Communication skills
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Nurse Practitioner
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Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 100 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
See 162 jobsAverage pay
St. Louis
$124,392 per yearMissouri
$126,207 per yearSkills
- Nursing
- Primary care
- Patient care
- EMR systems
- Communication skills
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Registered Nurse - Operating Room
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Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 90 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
See 51 jobsAverage pay
St. Louis
$2,374 per weekMissouri
$2,140 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 59 days on average from job posting to starting date. Currently, 23% of job openings are part-time roles.
See 485 jobsAverage pay
St. Louis
$2,117 per weekMissouri
$1,585 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Medical/Surgical
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Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
See 116 jobsAverage pay
St. Louis
$1,998 per weekMissouri
$1,971 per week -
Nursing Supervisor
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Nursing Supervisors oversee nursing staff, ensure patient care standards, and coordinate shifts. Leadership skills, clinical expertise, and proficiency in healthcare regulations are essential.
Nursing Supervisor jobs take 42 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See 69 jobsAverage pay
St. Louis
$44.25 per hourMissouri
$40.07 per hourSkills
- Supervising experience
- Team management
- Nursing
- Medical terminology
- Medical records
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Clinical Nurse
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Clinical nurses administer treatments, assess patient needs and collaborate with healthcare teams. Proficiency in clinical procedures, strong assessment skills and compassion are essential.
Clinical Nurse jobs take 42 days on average from job posting to starting date. Currently, 14% of job openings are part-time roles.
See 104 jobsAverage pay
St. Louis
$38.51 per hourMissouri
$37.08 per hour -
Charge Nurse
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Charge nurses lead nursing teams, coordinate patient care and manage staff schedules. Key qualifications include maintaining a registered nurse license, leadership skills and strong clinical expertise.
Charge Nurse jobs take 74 days on average from job posting to starting date. Currently, 16% of job openings are part-time roles.
See 60 jobsAverage pay
St. Louis
$36.37 per hourMissouri
$34.47 per hourSkills
- Nursing
- Medical documentation
- Medical records
- Physiology knowledge
- Medical terminology
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Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
Licensed Practical Nurse jobs take 55 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
See 348 jobsAverage pay
St. Louis
$32.73 per hourMissouri
$32.15 per hourSkills
- Nursing
- Medication administration
- Patient care
- Care plans
- Patient monitoring
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Nursing Assistant
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Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 56 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
See 247 jobsAverage pay
St. Louis
$19.57 per hourMissouri
$18.86 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records