High-paying nursing jobs in St. Louis
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 2,610 nursing jobs listed below pay well, with salaries between $44,463 and $130,911 per year. Registered Nurse, Clinical Nurse and Licensed Practical Nurse are among the most popular high-paying roles in St. Louis, MO.
Job title
Updated Oct 03, 2026Registered Nurse - Operating Room
St. Louis
Missouri
Nurse Practitioner
St. Louis
Missouri
Registered Nurse - Icu
St. Louis
Missouri
Registered Nurse
St. Louis
Missouri
Registered Nurse - Medical/Surgical
St. Louis
Missouri
Nursing Supervisor
St. Louis
Missouri
Clinical Nurse
St. Louis
Missouri
Nurse
St. Louis
Missouri
Licensed Practical Nurse
St. Louis
Missouri
Nursing Assistant
St. Louis
Missouri
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Registered Nurse - Operating Room
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Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 96 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
See 143 jobsAverage pay
St. Louis
$2,395 per weekMissouri
$2,159 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Nurse Practitioner
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Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 100 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 21% of job openings are part-time roles.
See 152 jobsAverage pay
St. Louis
$124,267 per yearMissouri
$126,465 per yearSkills
- Nursing
- Primary care
- Patient care
- EMR systems
- Communication skills
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Registered Nurse - Icu
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ICU Registered Nurses monitor patient vitals, administer medication, and provide critical care support. Expertise in critical patient care, strong clinical judgment, and certifications are key.
Registered Nurse - Icu jobs take 40 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
See 122 jobsAverage pay
St. Louis
$2,143 per weekMissouri
$2,069 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- ICU experience
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 59 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See 618 jobsAverage pay
St. Louis
$2,114 per weekMissouri
$2,084 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Medical/Surgical
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Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
See 168 jobsAverage pay
St. Louis
$1,999 per weekMissouri
$1,968 per week -
Nursing Supervisor
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Nursing Supervisors oversee nursing staff, ensure patient care standards, and coordinate shifts. Leadership skills, clinical expertise, and proficiency in healthcare regulations are essential.
Nursing Supervisor jobs take 45 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See 96 jobsAverage pay
St. Louis
$43.57 per hourMissouri
$39.77 per hourSkills
- Supervising experience
- Team management
- Nursing
- Medical terminology
- Medical records
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Clinical Nurse
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Clinical nurses administer treatments, assess patient needs and collaborate with healthcare teams. Proficiency in clinical procedures, strong assessment skills and compassion are essential.
Clinical Nurse jobs take 42 days on average from job posting to starting date. Currently, 15% of job openings are part-time roles.
See 496 jobsAverage pay
St. Louis
$38.66 per hourMissouri
$36.86 per hour -
Nurse
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Nurses administer patient care, monitor health conditions, and collaborate with healthcare teams. Nursing qualification, empathy, and strong clinical skills are essential.
Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See 141 jobsAverage pay
St. Louis
$33.99 per hourMissouri
$33.22 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Medical terminology
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Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
Licensed Practical Nurse jobs take 55 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
See 377 jobsAverage pay
St. Louis
$32.82 per hourMissouri
$32.22 per hourSkills
- Nursing
- Medication administration
- Patient care
- Care plans
- Patient monitoring
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Nursing Assistant
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Please refer to the employers job description for complete details.
Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 55 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
See 297 jobsAverage pay
St. Louis
$19.68 per hourMissouri
$18.92 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records