Nurse practitioner salary in Indianapolis, IN

The average salary for a Nurse Practitioner is $125,084 per year in Indianapolis, IN. This figure is based on 148 salaries taken from job postings on Indeed in the past 36 months, last updated on September 3, 2026.

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Nurse Practitioner salaries in Indianapolis, IN typically range between a low of $67,957 and a high of $189,041 per year, depending on experience and the hiring company.

Some of the highest-paying cities for Nurse Practitioner in Indianapolis, IN include Fort Wayne, IN at $127,112 per year, Jeffersonville, IN at $126,703 per year, and Lafayette, IN at $125,625 per year.

Based on recent job postings on Indeed, some of the top-paying companies for Nurse Practitioner in Indianapolis, IN include VitalCheck Wellness ($258,700 per year) and Provenir Healthcare ($239,200 per year).

Compensation can vary based on the specific niche and level of responsibility within the field. Here is how the average Nurse Practitioner salary in Indianapolis, IN compares to related positions:

• Lead Nurse Practitioner: Average $140,100 per year
• Nurse Practitioner II: Average $66.05 per hour
• Senior Nurse Practitioner: Average $117,591 per year