Registered nurse salary in St. Louis, MO
How much does a Registered Nurse make in St. Louis, MO?
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The average salary for a registered nurse is $41.46 per hour in St. Louis, MO and $12,000 overtime per year.832 salaries taken from job postings on Indeed in the past 36 months (updated November 1, 2026).
Highest paying companies for Registered Nurse in St. Louis, MO
Average year pay is based on job postings on Indeed in the past 36 months.Looking to Hire?
Highest paying cities for Registered Nurses near St. Louis, MO
Where can a Registered Nurse earn more?
Compare salaries for Registered Nurses in different locations
Frequently Asked Questions (FAQs) about Registered Nurse
The average salary for a Registered Nurse is $41.46 per hour in St. Louis, MO. This figure is based on 1.9k salaries taken from job postings on Indeed in the past 36 months, last updated on November 1, 2026.
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Registered Nurse salaries in St. Louis, MO typically range between a low of $43.65 and a high of $67.54 per hour, depending on experience and the hiring company.
Some of the highest-paying cities for Registered Nurse in St. Louis, MO include Kansas City, MO at $52.84 per hour, Cape Girardeau, MO at $52.47 per hour, and Springfield, MO at $52.27 per hour.
Based on recent job postings on Indeed, some of the top-paying companies for Registered Nurse in St. Louis, MO include Aspen Medical ($181,140 per year) and Opusing LLC ($174,633 per year).
Compensation can vary based on the specific niche and level of responsibility within the field. Here is how the average Registered Nurse salary in St. Louis, MO compares to related positions: