High-paying nursing jobs in Durham
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 825 nursing jobs listed below pay well, with salaries between $18.27 and $37.44 per hour. Registered Nurse, Nursing Assistant and Licensed Practical Nurse are among the most popular high-paying roles in Durham, NC.
Job title
Updated Oct 25, 2026Nurse Practitioner
Durham
North Carolina
Advanced Practice Provider
Durham
North Carolina
Registered Nurse - Operating Room
Durham
North Carolina
Registered Nurse
Durham
North Carolina
Registered Nurse - Emergency Room
Durham
North Carolina
Nurse Manager
Durham
North Carolina
Registered Nurse - Home Health
Durham
North Carolina
Senior Clinical Nurse
Durham
North Carolina
Licensed Practical Nurse
Durham
North Carolina
Nursing Assistant
Durham
North Carolina
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Nurse Practitioner
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Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
The top companies hiring Nurse Practitioner in Durham, NC are Duke Health (28 jobs), Lincoln Community Health Center (2 jobs), and DOCS Health (2 jobs).
Nurse Practitioner jobs take 100 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
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Durham
$142,309 per yearNorth Carolina
$120,876 per year -
Advanced Practice Provider
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Advanced practice providers deliver advanced clinical care, conduct patient assessments and collaborate with physicians to develop treatment plans. They need clinical expertise, knowledge of healthcare protocols and strong communication skills.
The top companies hiring Advanced Practice Provider in Durham, NC are Duke Health (6 jobs), Oak Street Health, part of CVS Health (1 job), and Avance Care (1 job).
Advanced Practice Provider jobs take 53 days on average from job posting to starting date. Currently, 13% of job openings are part-time roles.
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Durham
$61.97 per hourNorth Carolina
$57.58 per hour -
Registered Nurse - Operating Room
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Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 110 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
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Durham
$2,213 per weekNorth Carolina
$2,094 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
The top companies hiring Registered Nurse in Durham, NC are Duke Health (46 jobs), RI International (7 jobs), and DaVita (6 jobs).
Registered Nurse jobs take 67 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Durham
$2,011 per weekNorth Carolina
$1,989 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Emergency Room
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ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
Registered Nurse - Emergency Room jobs take 45 days on average from job posting to starting date. Currently, 13% of job openings are part-time roles.
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Durham
$1,949 per weekNorth Carolina
$1,855 per weekSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
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Nurse Manager
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Nurse Managers supervise nursing staff, develop care standards, and manage department budgets. Key skills include leadership expertise, clinical knowledge, and financial management.
Nurse Manager jobs take 44 days on average from job posting to starting date. Currently, 3% of job openings are part-time roles.
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Durham
$45.77 per hourNorth Carolina
$42.62 per hour -
Registered Nurse - Home Health
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Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
The top companies hiring Registered Nurse - Home Health in Durham, NC are Well Care Health (5 jobs), Duke Health (4 jobs), and BAYADA Home Health Care (3 jobs).
Registered Nurse - Home Health jobs take 57 days on average from job posting to starting date. Currently, 29% of job openings are part-time roles.
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Durham
$45.18 per hourNorth Carolina
$62.38 per hour -
Senior Clinical Nurse
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Senior clinical nurses plan patient care strategies, supervise nursing staff and manage complex cases. Advanced clinical expertise, excellent leadership skills and in-depth knowledge of patient care are essential in this role.
Senior Clinical Nurse jobs take 8 days on average from job posting to starting date. Currently, 26% of job openings are part-time roles.
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Durham
$37.44 per hourNorth Carolina
$16.36 per hour -
Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
The top companies hiring Licensed Practical Nurse in Durham, NC are Duke Health (5 jobs), PruittHealth (3 jobs), and RI International (3 jobs).
Licensed Practical Nurse jobs take 57 days on average from job posting to starting date. Currently, 33% of job openings are part-time roles.
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Durham
$33.18 per hourNorth Carolina
$32.96 per hour -
Nursing Assistant
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Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
The top companies hiring Nursing Assistant in Durham, NC are North Carolina Specialty Hospital (4 jobs), Duke Health (3 jobs), and Griswold (3 jobs).
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
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Durham
$18.27 per hourNorth Carolina
$17.74 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records