High-paying nursing jobs in San Mateo
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 838 nursing jobs listed below pay well, with salaries between $28.55 and $75.20 per hour. Nurse Practitioner, Registered Nurse and Licensed Vocational Nurse are among the most popular high-paying roles in San Mateo, CA.
Job title
Updated Oct 30, 2026
Job title
San Mateo, CA
California
Job openings (San Mateo)
Nurse Practitioner
San Mateo
$85.18
per hour
California
$107
per hour
Hospice Nurse
San Mateo
$75.20
per hour
California
$62.42
per hour
Registered Nurse Case Manager
San Mateo
$74.60
per hour
California
$74.90
per hour
Registered Nurse - Operating Room
San Mateo
$2,946
per week
California
$2,626
per week
Travel Nurse
San Mateo
$2,674
per week
California
$2,347
per week
Registered Nurse - Home Health
San Mateo
$135,224
per year
California
$125,772
per year
Registered Nurse II
San Mateo
$57.90
per hour
California
$72.57
per hour
Registered Nurse
San Mateo
$57.67
per hour
California
$55.86
per hour
Licensed Vocational Nurse
San Mateo
$40.58
per hour
California
$36.32
per hour
Home Health Aide
San Mateo
$28.55
per hour
California
$28.49
per hour
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
-
Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 100 days on average from job posting to starting date. Currently, 11% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
See jobsAverage pay
San Mateo
$85.18 per hourCalifornia
$107 per hour -
Hospice Nurse
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Please refer to the employers job description for complete details.
Hospice nurses provide compassionate care to terminally ill patients, managing symptoms and supporting families. Expertise in palliative care, strong emotional resilience and nursing licensure are key qualifications.
Hospice Nurse jobs take 82 days on average from job posting to starting date. Currently, 17% of job openings are part-time roles.
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San Mateo
$75.20 per hourCalifornia
$62.42 per hour -
Registered Nurse Case Manager
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RN Case Managers coordinate patient care plans, assess treatment options, and collaborate with healthcare teams. Expertise in case management, strong assessment skills, and communication abilities are essential.
Registered Nurse Case Manager jobs take 63 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
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San Mateo
$74.60 per hourCalifornia
$74.90 per hour -
Registered Nurse - Operating Room
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Please refer to the employers job description for complete details.
Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 110 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
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San Mateo
$2,946 per weekCalifornia
$2,626 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
-
Travel Nurse
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Please refer to the employers job description for complete details.
Travel Nurses provide healthcare services in various locations, adapt to new environments, and ensure patient care standards. Nursing credential, flexibility, and strong clinical skills are crucial.
Travel Nurse jobs take 43 days on average from job posting to starting date. Currently, 3% of job openings are part-time roles.
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San Mateo
$2,674 per weekCalifornia
$2,347 per week -
Registered Nurse - Home Health
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Please refer to the employers job description for complete details.
Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 58 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
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San Mateo
$135,224 per yearCalifornia
$125,772 per year -
Registered Nurse II
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Please refer to the employers job description for complete details.
Registered nurses provide patient care, administer medications and collaborate with healthcare teams. Nursing expertise, strong communication skills and licensure as a registered nurse are required.
Currently, 20% of job openings are part-time roles.
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San Mateo
$57.90 per hourCalifornia
$72.57 per hour -
Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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San Mateo
$57.67 per hourCalifornia
$55.86 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
-
Licensed Vocational Nurse
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Please refer to the employers job description for complete details.
Licensed Vocational Nurses provide patient care, administer medications, and document treatments. Clinical knowledge, empathy, and attention to procedural details are critical for ensuring patient well-being.
Licensed Vocational Nurse jobs take 58 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
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San Mateo
$40.58 per hourCalifornia
$36.32 per hour -
Home Health Aide
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Please refer to the employers job description for complete details.
Home health aides assist patients with daily activities, monitor conditions and provide companionship. Skills in personal care, empathy and the ability to follow care plans are essential in this role.
Home Health Aide jobs take 82 days on average from job posting to starting date. Currently, 60% of job openings are part-time roles.
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San Mateo
$28.55 per hourCalifornia
$28.49 per hour