High-paying nursing jobs in Simpsonville

Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.


The 598 nursing jobs listed below pay well, with salaries between $34,426 and $211,130 per year. Registered Nurse, Nursing Assistant and Licensed Practical Nurse are among the most popular high-paying roles in Simpsonville, SC.

Job title

Updated Oct 26, 2026
Job title
Simpsonville, SC
South Carolina
Job openings (Simpsonville)

Registered Nurse - Operating Room

Simpsonville

$2,174 per week

South Carolina

$1,963 per week

Registered Nurse

Simpsonville

$1,947 per week

South Carolina

$1,823 per week

Registered Nurse - Medical/Surgical

Simpsonville

$1,817 per week

South Carolina

$1,809 per week

Registered Nurse - Telemetry

Simpsonville

$1,728 per week

South Carolina

$1,775 per week

Registered Nurse - Acute Care

Simpsonville

$42.83 per hour

South Carolina

$36.47 per hour

Registered Nurse - Home Health

Simpsonville

$78,658 per year

South Carolina

$60,646 per year

Registered Nurse Manager

Simpsonville

$77,366 per year

South Carolina

$100,892 per year

Licensed Practical Nurse

Simpsonville

$29.32 per hour

South Carolina

$31.23 per hour

Nursing Assistant

Simpsonville

$15.24 per hour

South Carolina

$17.13 per hour

Nurse Practitioner

Simpsonville

$430 per day

South Carolina

$252 per day

Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.