High-paying nursing jobs in Simpsonville
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 378 nursing jobs listed below pay well, with salaries between $35,049 and $243,725 per year. Nursing Assistant, Licensed Practical Nurse and Nurse Practitioner are among the most popular high-paying roles in Simpsonville, SC.
Job title
Updated Sep 26, 2026Registered Nurse - Medical/Surgical
Simpsonville
South Carolina
Registered Nurse - Home Health
Simpsonville
South Carolina
Licensed Practical Nurse
Simpsonville
South Carolina
Nursing Assistant
Simpsonville
South Carolina
Nurse Practitioner
Simpsonville
South Carolina
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Registered Nurse - Medical/Surgical
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Please refer to the employers job description for complete details.
Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
See 7 jobsAverage pay
Simpsonville
$1,824 per weekSouth Carolina
$1,800 per week -
Registered Nurse - Home Health
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Please refer to the employers job description for complete details.
Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 62 days on average from job posting to starting date. Currently, 27% of job openings are part-time roles.
See 18 jobsAverage pay
Simpsonville
$78,658 per yearSouth Carolina
$61,460 per yearSkills
- Nursing
- Patient care
- Medication administration
- Home health
- Care plans
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Licensed Practical Nurse
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Please refer to the employers job description for complete details.
Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
Licensed Practical Nurse jobs take 55 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
See 116 jobsAverage pay
Simpsonville
$29.26 per hourSouth Carolina
$31.19 per hourSkills
- Nursing
- Medication administration
- Patient care
- Care plans
- Patient monitoring
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Nursing Assistant
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Please refer to the employers job description for complete details.
Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 55 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
See 186 jobsAverage pay
Simpsonville
$15.52 per hourSouth Carolina
$17.12 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records
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Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 102 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 21% of job openings are part-time roles.
See 51 jobsAverage pay
Simpsonville
$497 per daySouth Carolina
$252 per daySkills
- Nursing
- Primary care
- Patient care
- EMR systems
- Communication skills