High-paying nursing jobs in Simpsonville
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 598 nursing jobs listed below pay well, with salaries between $34,426 and $211,130 per year. Registered Nurse, Nursing Assistant and Licensed Practical Nurse are among the most popular high-paying roles in Simpsonville, SC.
Job title
Updated Oct 26, 2026Registered Nurse - Operating Room
Simpsonville
South Carolina
Registered Nurse
Simpsonville
South Carolina
Registered Nurse - Medical/Surgical
Simpsonville
South Carolina
Registered Nurse - Telemetry
Simpsonville
South Carolina
Registered Nurse - Acute Care
Simpsonville
South Carolina
Registered Nurse - Home Health
Simpsonville
South Carolina
Registered Nurse Manager
Simpsonville
South Carolina
Licensed Practical Nurse
Simpsonville
South Carolina
Nursing Assistant
Simpsonville
South Carolina
Nurse Practitioner
Simpsonville
South Carolina
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Registered Nurse - Operating Room
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Please refer to the employers job description for complete details.
Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 110 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
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Simpsonville
$2,174 per weekSouth Carolina
$1,963 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Registered Nurse
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Please refer to the employers job description for complete details.
Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 67 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Simpsonville
$1,947 per weekSouth Carolina
$1,823 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Medical/Surgical
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Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
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Simpsonville
$1,817 per weekSouth Carolina
$1,809 per week -
Registered Nurse - Telemetry
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Registered Nurses - Telemetry monitor patients, administer medications, and collaborate with healthcare teams. RN licensure, proficiency in telemetry, and critical thinking skills are essential.
Registered Nurse - Telemetry jobs take 21 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
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Simpsonville
$1,728 per weekSouth Carolina
$1,775 per week -
Registered Nurse - Acute Care
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Registered nurses in acute care monitor patient status, coordinate treatments and administer medications. Essential skills include acute care experience, clinical knowledge and patient-centered focus.
Registered Nurse - Acute Care jobs take 70 days on average from job posting to starting date. Currently, 18% of job openings are part-time roles.
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Simpsonville
$42.83 per hourSouth Carolina
$36.47 per hour -
Registered Nurse - Home Health
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Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 58 days on average from job posting to starting date. Currently, 29% of job openings are part-time roles.
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Simpsonville
$78,658 per yearSouth Carolina
$60,646 per year -
Registered Nurse Manager
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Registered nurse managers oversee nursing staff, manage budgets and ensure quality patient care. Leadership skills, RN licensure and experience in healthcare management are essential qualifications for this role.
Registered Nurse Manager jobs take 56 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
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Simpsonville
$77,366 per yearSouth Carolina
$100,892 per year -
Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
Licensed Practical Nurse jobs take 57 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
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Simpsonville
$29.32 per hourSouth Carolina
$31.23 per hour -
Nursing Assistant
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Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
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Simpsonville
$15.24 per hourSouth Carolina
$17.13 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records
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Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 100 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
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Simpsonville
$430 per daySouth Carolina
$252 per day