High-paying nursing jobs in Wilmington
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 1,283 nursing jobs listed below pay well, with salaries between $45,099 and $291,679 per year. Registered Nurse, Nursing Assistant and Licensed Practical Nurse are among the most popular high-paying roles in Wilmington, DE.
Job title
Updated Oct 28, 2026Certified Registered Nurse Anesthetist
Wilmington
Delaware
Psychiatric-mental Health Nurse Practitioner
Wilmington
Delaware
Nurse Practitioner
Wilmington
Delaware
Registered Nurse - Emergency Room
Wilmington
Delaware
Advanced Practice Provider
Wilmington
Delaware
Nursing Supervisor
Wilmington
Delaware
Registered Nurse
Wilmington
Delaware
Registered Nurse - Home Health
Wilmington
Delaware
Licensed Practical Nurse
Wilmington
Delaware
Nursing Assistant
Wilmington
Delaware
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Certified Registered Nurse Anesthetist
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Please refer to the employers job description for complete details.
Certified Registered Nurse Anesthetists administer anesthesia, monitor patients, and collaborate with surgeons. Expertise in anesthesia practices, clinical proficiency, and attention to safety are crucial.
Certified Registered Nurse Anesthetist jobs take 70 days on average from job posting to starting date. Currently, 16% of job openings are part-time roles.
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Wilmington
$291,679 per yearDelaware
$265,804 per year -
Psychiatric-mental Health Nurse Practitioner
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Psychiatric-mental health nurse practitioners diagnose disorders, prescribe treatments and support patients. Advanced nursing expertise, empathetic communication and licensure are essential in this role.
Psychiatric-mental Health Nurse Practitioner jobs take 92 days on average from job posting to starting date. Currently, 57% of job openings offer remote or hybrid positions and 24% of job openings are part-time roles.
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Wilmington
$199,694 per yearDelaware
$209,272 per year -
Nurse Practitioner
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Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 99 days on average from job posting to starting date. Currently, 11% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
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Wilmington
$143,787 per yearDelaware
$136,052 per year -
Registered Nurse - Emergency Room
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ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
Registered Nurse - Emergency Room jobs take 50 days on average from job posting to starting date. Currently, 14% of job openings are part-time roles.
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Wilmington
$53.03 per hourDelaware
$81.77 per hourSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
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Advanced Practice Provider
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Advanced practice providers deliver advanced clinical care, conduct patient assessments and collaborate with physicians to develop treatment plans. They need clinical expertise, knowledge of healthcare protocols and strong communication skills.
Advanced Practice Provider jobs take 53 days on average from job posting to starting date. Currently, 13% of job openings are part-time roles.
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Wilmington
$102,602 per yearDelaware
$132,735 per year -
Nursing Supervisor
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Nursing Supervisors oversee nursing staff, ensure patient care standards, and coordinate shifts. Leadership skills, clinical expertise, and proficiency in healthcare regulations are essential.
Nursing Supervisor jobs take 53 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Wilmington
$48.24 per hourDelaware
$46.65 per hourSkills
- Supervising experience
- Team management
- Nursing
- Medical terminology
- Medical records
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
Registered Nurse jobs take 67 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Wilmington
$47.94 per hourDelaware
$46.96 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Home Health
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Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
Registered Nurse - Home Health jobs take 58 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
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Wilmington
$40.76 per hourDelaware
$37.07 per hour -
Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
Licensed Practical Nurse jobs take 57 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
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Wilmington
$33.35 per hourDelaware
$34.56 per hour -
Nursing Assistant
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Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
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Wilmington
$19.97 per hourDelaware
$19.45 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records