High-paying nursing jobs in Greenville
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 556 nursing jobs listed below pay well, with salaries between $38,782 and $123,430 per year. Nursing Assistant, Registered Nurse and Licensed Practical Nurse are among the most popular high-paying roles in Greenville, SC.
Job title
Updated Nov 10, 2026Registered Nurse - Emergency Room
Greenville
South Carolina
Advanced Practice Provider
Greenville
South Carolina
Nurse Practitioner
Greenville
South Carolina
Registered Nurse - Acute Care
Greenville
South Carolina
Registered Nurse - Medical/Surgical
Greenville
South Carolina
Registered Nurse
Greenville
South Carolina
Registered Nurse - Pediatrics
Greenville
South Carolina
Registered Nurse - Home Health
Greenville
South Carolina
Licensed Practical Nurse
Greenville
South Carolina
Nursing Assistant
Greenville
South Carolina
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Registered Nurse - Emergency Room
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ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
Registered Nurse - Emergency Room jobs take 51 days on average from job posting to starting date. Currently, 15% of job openings are part-time roles.
See jobsAverage pay
Greenville
$123,430 per yearSouth Carolina
$100,395 per yearSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
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Advanced Practice Provider
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Advanced practice providers deliver advanced clinical care, conduct patient assessments and collaborate with physicians to develop treatment plans. They need clinical expertise, knowledge of healthcare protocols and strong communication skills.
The top companies hiring Advanced Practice Provider in Greenville, SC are Vituity (5 jobs), Commonwealth Pain & Spine (2 jobs), and Oak Street Health, part of CVS Health (1 job).
Advanced Practice Provider jobs take 51 days on average from job posting to starting date. Currently, 12% of job openings are part-time roles.
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Greenville
$119,441 per yearSouth Carolina
$116,737 per year -
Nurse Practitioner
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Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
The top companies hiring Nurse Practitioner in Greenville, SC are Prisma Health (11 jobs), Your Health Organization (4 jobs), and Jackson and Coker (2 jobs).
Nurse Practitioner jobs take 97 days on average from job posting to starting date. Currently, 15% of job openings offer remote or hybrid positions and 20% of job openings are part-time roles.
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Greenville
$114,703 per yearSouth Carolina
$123,755 per year -
Registered Nurse - Acute Care
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Registered nurses in acute care monitor patient status, coordinate treatments and administer medications. Essential skills include acute care experience, clinical knowledge and patient-centered focus.
Registered Nurse - Acute Care jobs take 64 days on average from job posting to starting date. Currently, 18% of job openings are part-time roles.
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Greenville
$1,916 per weekSouth Carolina
$2,046 per week -
Registered Nurse - Medical/Surgical
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Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
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Greenville
$1,795 per weekSouth Carolina
$1,814 per week -
Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
The top companies hiring Registered Nurse in Greenville, SC are Prisma Health (25 jobs), Bon Secours (11 jobs), and Saber Healthcare Group (4 jobs).
Registered Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Greenville
$40.84 per hourSouth Carolina
$46.82 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Pediatrics
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Pediatric RNs administer care to children, educate families and coordinate with healthcare teams. Specialized pediatric nursing skills, empathy and strong communication abilities are essential.
The top companies hiring Registered Nurse - Pediatrics in Greenville, SC are Prisma Health (8 jobs), Shriners Children's (2 jobs), and Samaritan Bed & Bath Service (1 job).
Registered Nurse - Pediatrics jobs take 39 days on average from job posting to starting date. Currently, 38% of job openings are part-time roles.
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Greenville
$39.53 per hourSouth Carolina
$41.38 per hour -
Registered Nurse - Home Health
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Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
The top companies hiring Registered Nurse - Home Health in Greenville, SC are Interim HealthCare (3 jobs), Angels of Care Pediatric Home Health (1 job), and Prisma Health (1 job).
Registered Nurse - Home Health jobs take 56 days on average from job posting to starting date. Currently, 29% of job openings are part-time roles.
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Greenville
$37.07 per hourSouth Carolina
$33.04 per hour -
Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
The top companies hiring Licensed Practical Nurse in Greenville, SC are Prisma Health (14 jobs), National HealthCare Corporation (3 jobs), and Saber Healthcare Group (3 jobs).
Licensed Practical Nurse jobs take 58 days on average from job posting to starting date. Currently, 33% of job openings are part-time roles.
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Greenville
$30.07 per hourSouth Carolina
$31.25 per hour -
Nursing Assistant
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Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
The top companies hiring Nursing Assistant in Greenville, SC are Prisma Health (34 jobs), Addus HomeCare (17 jobs), and Senior Helpers (3 jobs).
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 42% of job openings are part-time roles.
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Greenville
$17.17 per hourSouth Carolina
$17.15 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records