High-paying nursing jobs in Bluffton
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 378 nursing jobs listed below pay well, with salaries between $41,274 and $160,707 per year. Registered Nurse, Licensed Practical Nurse and Nursing Assistant are among the most popular high-paying roles in Bluffton, SC.
Job title
Updated Oct 17, 2026Nurse Practitioner
Bluffton
South Carolina
Advanced Practice Provider
Bluffton
South Carolina
Registered Nurse - Home Health
Bluffton
South Carolina
Registered Nurse - Medical/Surgical
Bluffton
South Carolina
Registered Nurse - Endoscopy
Bluffton
South Carolina
Registered Nurse - Emergency Room
Bluffton
South Carolina
Registered Nurse
Bluffton
South Carolina
Licensed Practical Nurse
Bluffton
South Carolina
Registered Nurse - Operating Room
Bluffton
South Carolina
Nursing Assistant
Bluffton
South Carolina
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
Nurse Practitioner jobs take 101 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
See 42 jobsAverage pay
Bluffton
$160,707 per yearSouth Carolina
$123,549 per year -
Advanced Practice Provider
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Advanced practice providers deliver advanced clinical care, conduct patient assessments and collaborate with physicians to develop treatment plans. They need clinical expertise, knowledge of healthcare protocols and strong communication skills.
Advanced Practice Provider jobs take 54 days on average from job posting to starting date. Currently, 13% of job openings are part-time roles.
See 13 jobsAverage pay
Bluffton
$63.31 per hourSouth Carolina
$58.76 per hour -
Registered Nurse - Home Health
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Registered Nurses - Home Health provide patient care, monitor health conditions, and liaise with healthcare teams. Nursing degree, licensure, and ability to work independently ensure quality patient support.
The top companies hiring Registered Nurse - Home Health in Bluffton, SC are Amedisys (6 jobs), Aveanna Healthcare (2 jobs), and Enhabit Home Health & Hospice (2 jobs).
Registered Nurse - Home Health jobs take 58 days on average from job posting to starting date. Currently, 28% of job openings are part-time roles.
See 30 jobsAverage pay
Bluffton
$2,144 per weekSouth Carolina
$1,109 per week -
Registered Nurse - Medical/Surgical
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Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
See 2 jobsAverage pay
Bluffton
$2,141 per weekSouth Carolina
$1,808 per week -
Registered Nurse - Endoscopy
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Registered nurses in endoscopy assist with procedures, monitor patient vitals and provide post-procedure care. Expertise in patient care, endoscopic procedures, and emergency response is essential in this role.
Registered Nurse - Endoscopy jobs take 65 days on average from job posting to starting date. Currently, 20% of job openings are part-time roles.
See 4 jobsAverage pay
Bluffton
$2,073 per weekSouth Carolina
$1,871 per week -
Registered Nurse - Emergency Room
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ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
Registered Nurse - Emergency Room jobs take 47 days on average from job posting to starting date. Currently, 13% of job openings are part-time roles.
See 15 jobsAverage pay
Bluffton
$2,030 per weekSouth Carolina
$1,832 per weekSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
The top companies hiring Registered Nurse in Bluffton, SC are Charleston ENT (3 jobs), St. Joseph's/Candler (1 job), and Encompass Health (1 job).
Registered Nurse jobs take 68 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
See 119 jobsAverage pay
Bluffton
$40.49 per hourSouth Carolina
$46.68 per hourSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
The top companies hiring Licensed Practical Nurse in Bluffton, SC are National HealthCare Corporation (5 jobs), Enhabit Home Health & Hospice (3 jobs), and Amedisys (2 jobs).
Licensed Practical Nurse jobs take 59 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
See 81 jobsAverage pay
Bluffton
$30.57 per hourSouth Carolina
$31.23 per hour -
Registered Nurse - Operating Room
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Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
Registered Nurse - Operating Room jobs take 105 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
See 9 jobsAverage pay
Bluffton
$24.88 per hourSouth Carolina
$50.62 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Nursing Assistant
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Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
The top companies hiring Nursing Assistant in Bluffton, SC are BrightStar Care (3 jobs), National HealthCare Corporation (2 jobs), and Encompass Health (1 job).
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
See 63 jobsAverage pay
Bluffton
$18.27 per hourSouth Carolina
$17.11 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records