High-paying nursing jobs in Bluffton

Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.


The 378 nursing jobs listed below pay well, with salaries between $41,274 and $160,707 per year. Registered Nurse, Licensed Practical Nurse and Nursing Assistant are among the most popular high-paying roles in Bluffton, SC.

Job title

Updated Oct 17, 2026
Job title
Bluffton, SC
South Carolina
Job openings (Bluffton)

Nurse Practitioner

Bluffton

$160,707 per year

South Carolina

$123,549 per year

Advanced Practice Provider

Bluffton

$63.31 per hour

South Carolina

$58.76 per hour

Registered Nurse - Home Health

Bluffton

$2,144 per week

South Carolina

$1,109 per week

Registered Nurse - Medical/Surgical

Bluffton

$2,141 per week

South Carolina

$1,808 per week

Registered Nurse - Endoscopy

Bluffton

$2,073 per week

South Carolina

$1,871 per week

Registered Nurse - Emergency Room

Bluffton

$2,030 per week

South Carolina

$1,832 per week

Registered Nurse

Bluffton

$40.49 per hour

South Carolina

$46.68 per hour

Licensed Practical Nurse

Bluffton

$30.57 per hour

South Carolina

$31.23 per hour

Registered Nurse - Operating Room

Bluffton

$24.88 per hour

South Carolina

$50.62 per hour

Nursing Assistant

Bluffton

$18.27 per hour

South Carolina

$17.11 per hour

Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.