High-paying nursing jobs in Charleston

Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.


The 354 nursing jobs listed below pay well, with salaries between $40,737 and $126,842 per year. Registered Nurse, Nursing Assistant and Licensed Practical Nurse are among the most popular high-paying roles in Charleston, SC.

Job title

Updated Oct 31, 2026
Job title
Charleston, SC
South Carolina
Job openings (Charleston)

Nurse Practitioner

Charleston

$85.99 per hour

South Carolina

$91.76 per hour

Advanced Practice Provider

Charleston

$126,842 per year

South Carolina

$117,292 per year

Travel Nurse

Charleston

$1,931 per week

South Carolina

$1,894 per week

Registered Nurse - Icu

Charleston

$1,928 per week

South Carolina

$1,892 per week

Registered Nurse - Operating Room

Charleston

$1,904 per week

South Carolina

$1,963 per week

Registered Nurse

Charleston

$1,831 per week

South Carolina

$1,823 per week

Registered Nurse - Emergency Room

Charleston

$1,712 per week

South Carolina

$1,828 per week

Registered Nurse - Medical/Surgical

Charleston

$1,640 per week

South Carolina

$1,809 per week

Licensed Practical Nurse

Charleston

$30.59 per hour

South Carolina

$31.23 per hour

Nursing Assistant

Charleston

$18.03 per hour

South Carolina

$17.13 per hour

Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.