High-paying nursing jobs in Charleston

Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.


The 416 nursing jobs listed below pay well, with salaries between $40,684 and $166,425 per year. Registered Nurse, Nursing Assistant and Licensed Practical Nurse are among the most popular high-paying roles in Charleston, SC.

Job title

Updated Nov 07, 2026
Job title
Charleston, SC
South Carolina
Job openings (Charleston)

Nurse Practitioner

Charleston

$85.31 per hour

South Carolina

$91.96 per hour

Psychiatric-mental Health Nurse Practitioner

Charleston

$166,425 per year

South Carolina

$147,284 per year

Advanced Practice Provider

Charleston

$126,842 per year

South Carolina

$116,584 per year

Registered Nurse - Icu

Charleston

$1,940 per week

South Carolina

$1,904 per week

Registered Nurse - Operating Room

Charleston

$1,909 per week

South Carolina

$1,969 per week

Registered Nurse

Charleston

$1,836 per week

South Carolina

$1,827 per week

Registered Nurse - Emergency Room

Charleston

$1,726 per week

South Carolina

$1,836 per week

Registered Nurse - Medical/Surgical

Charleston

$1,644 per week

South Carolina

$1,814 per week

Licensed Practical Nurse

Charleston

$30.49 per hour

South Carolina

$31.25 per hour

Nursing Assistant

Charleston

$18.01 per hour

South Carolina

$17.16 per hour

Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.