High-paying nursing jobs in Charleston
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 354 nursing jobs listed below pay well, with salaries between $40,737 and $126,842 per year. Registered Nurse, Nursing Assistant and Licensed Practical Nurse are among the most popular high-paying roles in Charleston, SC.
Job title
Updated Oct 31, 2026Nurse Practitioner
Charleston
South Carolina
Advanced Practice Provider
Charleston
South Carolina
Travel Nurse
Charleston
South Carolina
Registered Nurse - Icu
Charleston
South Carolina
Registered Nurse - Operating Room
Charleston
South Carolina
Registered Nurse
Charleston
South Carolina
Registered Nurse - Emergency Room
Charleston
South Carolina
Registered Nurse - Medical/Surgical
Charleston
South Carolina
Licensed Practical Nurse
Charleston
South Carolina
Nursing Assistant
Charleston
South Carolina
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
The top companies hiring Nurse Practitioner in Charleston, SC are Restore Hyper Wellness (2 jobs), West Coast Wound & Skin Care (2 jobs), and Matrix Medical Network (1 job).
Nurse Practitioner jobs take 99 days on average from job posting to starting date. Currently, 10% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
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Charleston
$85.99 per hourSouth Carolina
$91.76 per hour -
Advanced Practice Provider
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Advanced practice providers deliver advanced clinical care, conduct patient assessments and collaborate with physicians to develop treatment plans. They need clinical expertise, knowledge of healthcare protocols and strong communication skills.
The top companies hiring Advanced Practice Provider in Charleston, SC are Trident Medical Center (2 jobs), TeamHealth (1 job), and Oak Street Health, part of CVS Health (1 job).
Advanced Practice Provider jobs take 53 days on average from job posting to starting date. Currently, 13% of job openings are part-time roles.
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Charleston
$126,842 per yearSouth Carolina
$117,292 per year -
Travel Nurse
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Travel Nurses provide healthcare services in various locations, adapt to new environments, and ensure patient care standards. Nursing credential, flexibility, and strong clinical skills are crucial.
The top companies hiring Travel Nurse in Charleston, SC are Voyage Health (12 jobs), American Traveler (5 jobs), and Medical Solutions (2 jobs).
Travel Nurse jobs take 43 days on average from job posting to starting date. Currently, 3% of job openings are part-time roles.
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Charleston
$1,931 per weekSouth Carolina
$1,894 per week -
Registered Nurse - Icu
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ICU Registered Nurses monitor patient vitals, administer medication, and provide critical care support. Expertise in critical patient care, strong clinical judgment, and certifications are key.
The top companies hiring Registered Nurse - Icu in Charleston, SC are Medical Solutions (8 jobs), American Traveler (6 jobs), and Trident Medical Center (4 jobs).
Registered Nurse - Icu jobs take 39 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
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Charleston
$1,928 per weekSouth Carolina
$1,892 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- ICU experience
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Registered Nurse - Operating Room
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Please refer to the employers job description for complete details.
Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
The top companies hiring Registered Nurse - Operating Room in Charleston, SC are American Traveler (11 jobs), Vibra Travels (6 jobs), and Medical Solutions (3 jobs).
Registered Nurse - Operating Room jobs take 109 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
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Charleston
$1,904 per weekSouth Carolina
$1,963 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
The top companies hiring Registered Nurse in Charleston, SC are Roper St. Francis Healthcare (31 jobs), Trident Medical Center (7 jobs), and HealthTrust Workforce Solutions (4 jobs).
Registered Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Charleston
$1,831 per weekSouth Carolina
$1,823 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Emergency Room
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ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
The top companies hiring Registered Nurse - Emergency Room in Charleston, SC are Novant Health (10 jobs), Roper St. Francis Healthcare (5 jobs), and Trident Medical Center (3 jobs).
Registered Nurse - Emergency Room jobs take 51 days on average from job posting to starting date. Currently, 15% of job openings are part-time roles.
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Charleston
$1,712 per weekSouth Carolina
$1,828 per weekSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
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Registered Nurse - Medical/Surgical
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Please refer to the employers job description for complete details.
Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
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Charleston
$1,640 per weekSouth Carolina
$1,809 per week -
Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
The top companies hiring Licensed Practical Nurse in Charleston, SC are Medical University of South Carolina (10 jobs), National HealthCare Corporation (4 jobs), and Vistelan Healthcare LLC (4 jobs).
Licensed Practical Nurse jobs take 58 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
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Charleston
$30.59 per hourSouth Carolina
$31.23 per hour -
Nursing Assistant
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Nursing Assistants assist with patient care, monitor vital signs, and support nursing staff. Compassionate demeanor, basic knowledge of medical procedures, and physical stamina are essential attributes.
The top companies hiring Nursing Assistant in Charleston, SC are Vistelan Healthcare LLC (7 jobs), BAYADA Home Health Care (2 jobs), and Ashley River Healthcare (2 jobs).
Nursing Assistant jobs take 59 days on average from job posting to starting date. Currently, 41% of job openings are part-time roles.
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Charleston
$18.03 per hourSouth Carolina
$17.13 per hourSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical records