High-paying nursing jobs in Des Moines
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 511 nursing jobs listed below pay well, with salaries between $61,003 and $155,947 per year. Registered Nurse, Registered Nurse - Medical/Surgical and Licensed Practical Nurse are among the most popular high-paying roles in Des Moines, IA.
Job title
Updated Nov 07, 2026Registered Nurse - Catheterization Lab
Des Moines
Iowa
Registered Nurse - Operating Room
Des Moines
Iowa
Nurse Practitioner
Des Moines
Iowa
Registered Nurse
Des Moines
Iowa
Registered Nurse - Acute Care
Des Moines
Iowa
Registered Nurse - Medical/Surgical
Des Moines
Iowa
Registered Nurse - Icu
Des Moines
Iowa
Registered Nurse - Emergency Room
Des Moines
Iowa
Travel Nurse
Des Moines
Iowa
Licensed Practical Nurse
Des Moines
Iowa
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Registered Nurse - Catheterization Lab
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Registered nurses in catheterization labs assist in heart diagnostics, monitor patient health and ensure procedural safety. Expertise in cardiac care, strong assessment skills and compassion are essential in this role.
The top companies hiring Registered Nurse - Catheterization Lab in Des Moines, IA are Fidelity On Call (4 jobs), American Traveler (3 jobs), and MercyOne (2 jobs).
Registered Nurse - Catheterization Lab jobs take 89 days on average from job posting to starting date. Currently, 8% of job openings are part-time roles.
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Des Moines
$2,853 per weekIowa
$2,771 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical terminology
- Laboratory experience
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Registered Nurse - Operating Room
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Please refer to the employers job description for complete details.
Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
The top companies hiring Registered Nurse - Operating Room in Des Moines, IA are MercyOne (13 jobs), Fidelity On Call (2 jobs), and UnityPoint Health (2 jobs).
Registered Nurse - Operating Room jobs take 112 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
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Des Moines
$2,527 per weekIowa
$2,444 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
The top companies hiring Nurse Practitioner in Des Moines, IA are Primary Health Care, Inc. (4 jobs), Optum (3 jobs), and Iowa Primary Care Association (2 jobs).
Nurse Practitioner jobs take 101 days on average from job posting to starting date. Currently, 13% of job openings offer remote or hybrid positions and 20% of job openings are part-time roles.
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Des Moines
$128,517 per yearIowa
$118,995 per year -
Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
The top companies hiring Registered Nurse in Des Moines, IA are MercyOne (38 jobs), UnityPoint Health (9 jobs), and Fresenius Medical Care (7 jobs).
Registered Nurse jobs take 67 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Des Moines
$2,321 per weekIowa
$2,160 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Acute Care
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Registered nurses in acute care monitor patient status, coordinate treatments and administer medications. Essential skills include acute care experience, clinical knowledge and patient-centered focus.
The top companies hiring Registered Nurse - Acute Care in Des Moines, IA are UnityPoint Health (20 jobs), MercyOne (3 jobs), and Prolink (1 job).
Registered Nurse - Acute Care jobs take 70 days on average from job posting to starting date. Currently, 18% of job openings are part-time roles.
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Des Moines
$2,262 per weekIowa
$2,273 per week -
Registered Nurse - Medical/Surgical
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Please refer to the employers job description for complete details.
Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
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Des Moines
$2,206 per weekIowa
$2,136 per week -
Registered Nurse - Icu
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ICU Registered Nurses monitor patient vitals, administer medication, and provide critical care support. Expertise in critical patient care, strong clinical judgment, and certifications are key.
The top companies hiring Registered Nurse - Icu in Des Moines, IA are American Traveler (18 jobs), White Glove Placement, Inc. (7 jobs), and MercyOne (6 jobs).
Registered Nurse - Icu jobs take 39 days on average from job posting to starting date. Currently, 11% of job openings are part-time roles.
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Des Moines
$2,195 per weekIowa
$2,191 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- ICU experience
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Registered Nurse - Emergency Room
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ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
The top companies hiring Registered Nurse - Emergency Room in Des Moines, IA are UnityPoint Health (6 jobs), MercyOne (6 jobs), and American Traveler (2 jobs).
Registered Nurse - Emergency Room jobs take 51 days on average from job posting to starting date. Currently, 15% of job openings are part-time roles.
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Des Moines
$2,167 per weekIowa
$2,125 per weekSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
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Travel Nurse
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Travel Nurses provide healthcare services in various locations, adapt to new environments, and ensure patient care standards. Nursing credential, flexibility, and strong clinical skills are crucial.
The top companies hiring Travel Nurse in Des Moines, IA are American Traveler (9 jobs), Fidelity On Call (5 jobs), and Soliant (2 jobs).
Travel Nurse jobs take 43 days on average from job posting to starting date. Currently, 3% of job openings are part-time roles.
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Des Moines
$2,113 per weekIowa
$2,015 per week -
Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
The top companies hiring Licensed Practical Nurse in Des Moines, IA are UnityPoint Health (4 jobs), Trinity Center (3 jobs), and CALVIN COMMUNITY (3 jobs).
Licensed Practical Nurse jobs take 58 days on average from job posting to starting date. Currently, 33% of job openings are part-time roles.
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Des Moines
$33.98 per hourIowa
$33.88 per hour