High-paying nursing jobs in Des Moines
Nursing is caring for patients and managing healthcare. Nurses provide essential support by monitoring patient conditions and administering treatments. They need empathy, attention to detail, and strong communication skills to deliver quality care.
The 478 nursing jobs listed below pay well, with salaries between $60,856 and $137,407 per year. Registered Nurse, Registered Nurse - Medical/Surgical and Licensed Practical Nurse are among the most popular high-paying roles in Des Moines, IA.
Job title
Updated Oct 30, 2026Registered Nurse - Operating Room
Des Moines
Iowa
Nurse Practitioner
Des Moines
Iowa
Nursing Supervisor
Des Moines
Iowa
Registered Nurse
Des Moines
Iowa
Registered Nurse - Acute Care
Des Moines
Iowa
Registered Nurse - Medical/Surgical
Des Moines
Iowa
Registered Nurse - Icu
Des Moines
Iowa
Registered Nurse - Emergency Room
Des Moines
Iowa
Travel Nurse
Des Moines
Iowa
Licensed Practical Nurse
Des Moines
Iowa
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Registered Nurse - Operating Room
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Registered Nurses in the Operating Room assist during surgeries, monitor patient status, and maintain sterile environments. Expertise in surgical procedures, attention to detail, and strong communication skills are essential.
The top companies hiring Registered Nurse - Operating Room in Des Moines, IA are MercyOne (12 jobs), Medical Solutions (9 jobs), and American Traveler (3 jobs).
Registered Nurse - Operating Room jobs take 110 days on average from job posting to starting date. Currently, 9% of job openings are part-time roles.
See jobsAverage pay
Des Moines
$2,514 per weekIowa
$2,440 per weekSkills
- Nursing
- Patient care
- Medical documentation
- Physiology knowledge
- Medical terminology
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Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose patients, prescribe medications, and collaborate with healthcare teams. Requires advanced clinical skills, autonomy in practice, and a valid NP license.
The top companies hiring Nurse Practitioner in Des Moines, IA are Optum (4 jobs), Iowa Primary Care Association (2 jobs), and Planned Parenthood (1 job).
Nurse Practitioner jobs take 100 days on average from job posting to starting date. Currently, 11% of job openings offer remote or hybrid positions and 22% of job openings are part-time roles.
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Des Moines
$128,734 per yearIowa
$118,307 per year -
Nursing Supervisor
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Please refer to the employers job description for complete details.
Nursing Supervisors oversee nursing staff, ensure patient care standards, and coordinate shifts. Leadership skills, clinical expertise, and proficiency in healthcare regulations are essential.
The top companies hiring Nursing Supervisor in Des Moines, IA are MercyOne (6 jobs), UnityPoint Health (4 jobs), and Orchard Place (1 job).
Nursing Supervisor jobs take 53 days on average from job posting to starting date. Currently, 23% of job openings are part-time roles.
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Des Moines
$2,365 per weekIowa
$1,893 per weekSkills
- Supervising experience
- Team management
- Nursing
- Medical terminology
- Medical records
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. Nursing licensure, clinical expertise, and strong communication skills are essential.
The top companies hiring Registered Nurse in Des Moines, IA are MercyOne (41 jobs), UnityPoint Health (9 jobs), and Fresenius Medical Care (6 jobs).
Registered Nurse jobs take 66 days on average from job posting to starting date. Currently, 24% of job openings are part-time roles.
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Des Moines
$2,319 per weekIowa
$2,160 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- Hindi
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Registered Nurse - Acute Care
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Registered nurses in acute care monitor patient status, coordinate treatments and administer medications. Essential skills include acute care experience, clinical knowledge and patient-centered focus.
The top companies hiring Registered Nurse - Acute Care in Des Moines, IA are UnityPoint Health (19 jobs), MercyOne (3 jobs), and Vibra Travels (1 job).
Registered Nurse - Acute Care jobs take 71 days on average from job posting to starting date. Currently, 18% of job openings are part-time roles.
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Des Moines
$2,223 per weekIowa
$2,255 per week -
Registered Nurse - Medical/Surgical
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Registered nurses in medical-surgical care provide patient care, monitor vitals and administer treatments. Expertise in nursing procedures, patient assessment, and emergency response is essential in this role.
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Des Moines
$2,205 per weekIowa
$2,130 per week -
Registered Nurse - Icu
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ICU Registered Nurses monitor patient vitals, administer medication, and provide critical care support. Expertise in critical patient care, strong clinical judgment, and certifications are key.
The top companies hiring Registered Nurse - Icu in Des Moines, IA are American Traveler (19 jobs), Medical Solutions (18 jobs), and White Glove Placement, Inc. (6 jobs).
Registered Nurse - Icu jobs take 40 days on average from job posting to starting date. Currently, 10% of job openings are part-time roles.
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Des Moines
$2,198 per weekIowa
$2,191 per weekSkills
- Nursing
- Patient care
- Physiology knowledge
- Medical documentation
- ICU experience
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Registered Nurse - Emergency Room
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Please refer to the employers job description for complete details.
ER Registered Nurses provide critical care, assess patient needs, and collaborate with healthcare teams under pressure. Expertise in emergency care, quick decision-making, and excellent communication skills are crucial for success.
The top companies hiring Registered Nurse - Emergency Room in Des Moines, IA are MercyOne (7 jobs), UnityPoint Health (4 jobs), and American Traveler (2 jobs).
Registered Nurse - Emergency Room jobs take 51 days on average from job posting to starting date. Currently, 14% of job openings are part-time roles.
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Des Moines
$2,167 per weekIowa
$2,126 per weekSkills
- Nursing
- Physiology knowledge
- Medical documentation
- Patient care
- Medical records
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Travel Nurse
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Travel Nurses provide healthcare services in various locations, adapt to new environments, and ensure patient care standards. Nursing credential, flexibility, and strong clinical skills are crucial.
The top companies hiring Travel Nurse in Des Moines, IA are Medical Solutions (26 jobs), American Traveler (9 jobs), and Soliant (2 jobs).
Travel Nurse jobs take 43 days on average from job posting to starting date. Currently, 3% of job openings are part-time roles.
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Des Moines
$2,103 per weekIowa
$2,012 per week -
Licensed Practical Nurse
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Licensed Practical Nurses provide patient care, monitor vital signs, and assist doctors. Nursing license, proficiency in medical equipment, and strong interpersonal skills are essential.
The top companies hiring Licensed Practical Nurse in Des Moines, IA are UnityPoint Health (4 jobs), Trinity Center (3 jobs), and Accura HealthCare (3 jobs).
Licensed Practical Nurse jobs take 58 days on average from job posting to starting date. Currently, 32% of job openings are part-time roles.
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Des Moines
$33.90 per hourIowa
$33.84 per hour